Tuberculosis (TB) is a devastating infectious disease that kills over a million people every
year. There is an increasing burden of multi drug resistance (MDR) and extensively drug …

Cell-to-cell communication is a fundamental process of bacteria to exert communal
behaviors. Sputum samples of patients with cystic fibrosis have often been observed with …

Mycobacterium bovis onco-BCG bacilli used in immunotherapy of bladder cancer are
candidates for training of immune cells towards microbial pathogens. Increasing antibiotic …

Cyclic di-GMP (c-di-GMP) is a second messenger that promotes biofilm formation in several
bacterial species, but the mechanisms are often unclear. Here, we report that c-di-GMP …

Abstract The vaccine Mycobacterium bovis Bacillus Calmette-Guérin (BCG) elicits an
immune response that is protective against certain forms of tuberculosis (TB); however …

The role of biofilms in pathogenicity and treatment strategies is often neglected in
mycobacterial infections. In recent years, the emergence of nontuberculous mycobacterial …

While Tuberculosis (TB) infection remains a serious challenge worldwide, big data and
“omic” approaches have greatly contributed to the understanding of the disease …

Mycobacterium bovis and other Mycobacterium tuberculosis complex (MTBC) pathogens
that cause domestic animal and wildlife tuberculosis have received considerably less …

The antibiotic-tolerant biofilms present in tuberculous granulomas add an additional layer of
complexity when treating mycobacterial infections, including tuberculosis (TB). For a more …

Mycobacteria naturally grow as corded biofilms in liquid media without detergent. Such
detergent-free biofilm phenotypes may reflect the growth pattern of bacilli in tuberculous …