Abstract Treatment of opioid use disorder (OUD) with buprenorphine has evolved
considerably in the last decade as the scale of the OUD epidemic has increased along with …

Buprenorphine possesses many unique attributes that make it a practical agent for adults
and adolescents with opioid use disorder (OUD) and/or acute or chronic pain. Sublingual …

Objectives: Buprenorphine can precipitate withdrawal in opioid-dependent persons with
recent fentanyl use. However, the prevalence of this phenomenon is not clinically …

Low dose buprenorphine initiation, is an alternative method of initiating buprenorphine in
which the starting dose is very low and gradually increased to therapeutic levels over a …

Buprenorphine induction for treating opioid use disorder is being implemented in
emergency care. During this era of high-potency synthetic opioid use, novel and divergent …

Objectives: Patients with opioid use disorder (OUD) can initiate buprenorphine without
requiring a withdrawal period through a low-dose (sometimes referred to as “micro …

Abstract Introduction and Aims North America is currently experiencing an epidemic of
opioid overdose deaths, driven by the proliferation of fentanyl in the street drug market …

Methadone, a full opioid agonist at the mu-, kappa-, and delta-receptor, and buprenorphine,
a partial agonist at the mu receptor, are first-line medications in opioid maintenance …

Objectives Buprenorphine treatment significantly reduces morbidity and mortality for people
with opioid use disorder. Fear of precipitated withdrawal remains a barrier to starting …

Background Opioid overdose remains a leading cause of death. Office-based
buprenorphine could expand access to treatment to the many opioid users who are not in …