2023 update on sepsis and septic shock in adult patients: management in the emergency department
Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …
requires timely management to reduce mortality. This review aims to update physicians with …
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …
[HTML][HTML] Impact of the timeliness of antibiotic therapy on the outcome of patients with sepsis and septic shock
SA Asner, F Desgranges, IT Schrijver, T Calandra - Journal of Infection, 2021 - Elsevier
Objectives To review the impact of the timeliness of antibiotic therapy on the outcome of
patients with sepsis or septic shock. Methods We searched MEDLINE, EMBASE, the …
patients with sepsis or septic shock. Methods We searched MEDLINE, EMBASE, the …
Sepsis performance improvement programs: from evidence toward clinical implementation
M Schinkel, PWB Nanayakkara, WJ Wiersinga - Critical Care, 2022 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2022. Other selected articles can be found online at https://www …
Emergency Medicine 2022. Other selected articles can be found online at https://www …
Medication and fluid management of pediatric sepsis and septic shock
L Burgunder, C Heyrend, J Olson, C Stidham, RD Lane… - Pediatric Drugs, 2022 - Springer
Sepsis is a life-threatening response to infection that contributes significantly to neonatal
and pediatric morbidity and mortality worldwide. The key tenets of care include early …
and pediatric morbidity and mortality worldwide. The key tenets of care include early …
Prehospital bundle of care based on antibiotic therapy and hemodynamic optimization is associated with a 30-day mortality decrease in patients with septic shock
R Jouffroy, B Gilbert, JP Tourtier… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: This study aims to investigate the association between the 30-day mortality in
patients with septic shock (SS) and a prehospital bundle of care completion, antibiotic …
patients with septic shock (SS) and a prehospital bundle of care completion, antibiotic …
[HTML][HTML] Towards understanding the effective use of antibiotics for sepsis
M Schinkel, K Paranjape, J Kundert, RSN Panday… - Chest, 2021 - Elsevier
Background The benefits of early antibiotics for sepsis have recently been questioned.
Evidence for this mainly comes from observational studies. The only randomized trial on this …
Evidence for this mainly comes from observational studies. The only randomized trial on this …
Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized …
H Rüddel, DO Thomas-Rüddel, K Reinhart, F Bach… - Critical Care, 2022 - Springer
Background Timely antimicrobial treatment and source control are strongly recommended
by sepsis guidelines, however, their impact on clinical outcomes is uncertain. Methods We …
by sepsis guidelines, however, their impact on clinical outcomes is uncertain. Methods We …
Prolonged length of stay in the emergency department and mortality in critically ill elderly patients with infections: A retrospective multicenter study
W Choi, SH Woo, DH Kim, JY Lee… - Emergency Medicine …, 2021 - Wiley Online Library
Background. This study aimed at investigating whether the length of stay (LOS) in the
emergency department (ED) is associated with mortality in elderly patients with infections …
emergency department (ED) is associated with mortality in elderly patients with infections …
The effect of fluid initiation timing on sepsis mortality: a meta-analysis
Objective Current guidelines suggest the immediate initiation of crystalloid for sepsis-
induced hypoperfusion but note that supporting evidence is low quality. The aim of this study …
induced hypoperfusion but note that supporting evidence is low quality. The aim of this study …