Refractory Crohn's disease: perspectives, unmet needs and innovations

L Bertin, M Crepaldi, M Zanconato… - Clinical and …, 2024 - Taylor & Francis
Crohn's disease (CD) is a complex, chronic inflammatory bowel disease characterized by
unpredictable flare-ups and periods of remission. Despite advances in treatment, CD …

Tissue engineering and regenerative medicine approaches in colorectal surgery

BB Mainali, JJ Yoo, MR Ladd - Annals of Coloproctology, 2024 - pmc.ncbi.nlm.nih.gov
Tissue engineering and regenerative medicine (TERM) is an emerging field that has
provided new therapeutic opportunities by delivering innovative solutions. The development …

The use of core descriptors from the ENiGMA code study in recent literature: a systematic review

SZ Khan, A Arline, KM Williams, MJ Lee… - Colorectal …, 2024 - Wiley Online Library
Aim The heterogeneity in data quality presented in studies regarding Crohn's anal fistula
(CAF) limit extrapolation into clinical practice. The ENiGMA collaborators established a core …

Effectiveness of autologous emulsified stromal vascular fraction tissue injection for the treatment of complex perianal fistulas in inflammatory bowel diseases patients …

AE Potenza, D Nachira, F Sacchetti… - Therapeutic …, 2024 - journals.sagepub.com
Complex fistulizing perianal disease is a disabling manifestation of inflammatory bowel
disease (IBD), seriously compromising patients 'quality of life'. The success rate of available …

[PDF][PDF] Local Transplantation of Mesenchymal Stromal Cells Is Safe and Could Alleviate Kienböck Disease's Complications: A Clinical Trial Study

B Sadri, N Labibzadeh, L Mirmorsali… - Cell Journal …, 2024 - celljournal.org
Objective: Kienböck disease is a rare condition characterized by severe pain and restricted
wrist movement. Variouspalliative methods have been proposed as therapeutic strategies …

Human adipose-derived mesenchymal stromal cells improved wound healing in enterocutaneous fistulizing disease mouse model

N Marsiano, Y Levi, P Schneider, I Schouten… - bioRxiv, 2024 - biorxiv.org
A significant complication of Crohn disease is the formation of perianal fistulas. While local
application of human adipose tissue-derived mesenchymal stromal cells (AT-MSC INN …

Efficacy and Safety of Stem Cell Therapy in the Treatment of Fistulizing Crohn's Disease and the Role of Autologous Stem Cell Transplantation: A Systematic Review

KL Gabriel, M Sami, O Ijishakin… - Journal of Advances …, 2023 - publish7promo.com
Background: Crohn's Disease (CD), especially its fistulizing form, presents significant
treatment challenges. Stem cell transplantation, particularly autologous stem cell …