Overproduced reactive oxygen and reactive nitrogen species (RONS) in the brain are
involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease …

Metal chelation can provide structural stability and form reactive centers in metalloproteins.
Approximately one third of known protein structures are metalloproteins, and metal binding …

Alzheimer's disease (AD) is a common neurodegenerative disease that brings about
enormous economic pressure to families and society. Inhibiting abnormal aggregation of Aβ …

Pathological pathways of Alzheimer's disease (AD) are criss-crossed, various pathological
factors are dynamically correlated and relatively independent, which makes the single-target …

The aberrant aggregation of amyloid-β (Aβ) peptides in the brain has been recognized as
the major hallmark of Alzheimer's disease (AD). Thus, the inhibition and dissociation of Aβ …

Alzheimer's disease (AD) is a major cause of dementia characterized by the overexpression
of transmembrane amyloid precursor protein and its neurotoxic byproduct amyloid beta (Aβ) …

By virtue of their small size, nanomaterials can cross the blood-brain barrier and, when
modified to target specific cells or regions, can achieve high bioavailability at the intended …

Abstract Two-dimensional (2D) materials have garnered significant attention due to their
ultrathin 2D structures with a high degree of anisotropy and functionality. Reliable …

The aggregation and deposition of neurotoxic Aβ fibrils are key in the etiology of Alzheimer's
disease (AD). It has been clinically recognized as a major form of dementia across the …

The unique nano–bio interfacial phenomena play a crucial role in the biosafety and
bioapplications of nanomaterials. As a representative two-dimensional (2D) nanomaterial …