Tea is one of the most consumed beverages in the world. Green tea, black tea, and oolong
tea are made from the same plant Camellia sinensis (L.) O. Kuntze. Among them, green tea …

Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

Neurodegenerative diseases exert an overwhelming socioeconomic burden all around the
globe. They are mainly characterized by modified protein accumulation that might trigger …

The dosage of the serine threonine kinase DYRK1A is critical in the central nervous system
(CNS) during development and aging. This review analyzes the functions of this kinase by …

Down syndrome (DS) is caused by trisomy of human chromosome 21 (Hsa21). The
understanding of genotype–phenotype relationships, the identification of driver genes and …

Obesity, which is caused by an energy imbalance between calorie intake and consumption,
has become a major international health burden. Obesity increases the risk of insulin …

Down syndrome (DS) is a genetic disease that occurs due to an aneuploidy of human
chromosome 21. Trisomy of chromosome 21 is a primary genetic cause of developmental …

Theanine, a major amino acid in green tea, exhibits a stress-reducing effect in mice and
humans. Matcha, which is essentially theanine-rich powdered green tea, is abundant in …

Using trio whole-exome sequencing, we have identified de novo heterozygous pathogenic
variants in GRIA4 in five unrelated individuals with intellectual disability and other …

In recent years, neurological and neurodegenerative disorders research has focused on
altered molecular mechanisms in search of potential pharmacological targets, eg …