The current status of de novo sequencing of peptides by MS/MS is reviewed with focus on
collision cell MS/MS spectra. The relation between peptide structure and observed fragment …

Biological research has focused in the past on model organisms and most of the functional
genomics studies in the field of plant sciences are still performed on model species or …

The European Medicines Agency received recently the first marketing authorization
application for a biosimilar monoclonal antibody (mAb) and adopted the final guidelines on …

The Consortium for Top-Down Proteomics (www. topdownproteomics. org) launched the
present study to assess the current state of top-down mass spectrometry (TD MS) and …

Animal venoms and toxins are now recognized as major sources of bioactive molecules that
may be tomorrow's new drug leads. Their complexity and their potential as drug sources …

Odorant-binding proteins (OBPs) and chemosensory proteins (CSPs) mediate both
perception and release of chemical stimuli in insects. The genome of the honey bee …

Revealing the metabolic abnormalities of central and peripheral systems in Alzheimer's
disease (AD) mouse model is of paramount importance for understanding AD disease …

Over the last years, top‐down (TD) MS has gained a remarkable space in proteomics,
rapidly trespassing the limit between a promising approach and a solid, established …

Abstract BACKGROUND MALDI-TOF mass spectrometry (MS) is set to make inroads into
clinical chemistry because it offers advantages over other analytical platforms. These …

The applications of organic matrices for matrix assisted laser desorption/ionization mass
spectrometry (MALDI-MS) are reviewed. Recent advances of MALDI-MS using organic …