Dietary carbohydrates and fats in nonalcoholic fatty liver disease

H Yki-Järvinen, PK Luukkonen, L Hodson… - Nature reviews …, 2021 - nature.com
The global prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …

Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors

S Francque, G Szabo, MF Abdelmalek… - Nature reviews …, 2021 - nature.com
The increasing epidemic of obesity worldwide is linked to serious health effects, including
increased prevalence of type 2 diabetes mellitus, cardiovascular disease and nonalcoholic …

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

E Buzzetti, M Pinzani, EA Tsochatzis - Metabolism, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

Mechanisms of non-alcoholic fatty liver disease in the metabolic syndrome. A narrative review

L Rinaldi, PC Pafundi, R Galiero, A Caturano… - Antioxidants, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are two different
entities sharing common clinical and physio-pathological features, with insulin resistance …

Added sugars and cardiovascular disease risk in children: a scientific statement from the American Heart Association

MB Vos, JL Kaar, JA Welsh, LV Van Horn, DI Feig… - Circulation, 2017 - Am Heart Assoc
Background: Poor lifestyle behaviors are leading causes of preventable diseases globally.
Added sugars contribute to a diet that is energy dense but nutrient poor and increase risk of …

[HTML][HTML] Metabolic drivers of non-alcoholic fatty liver disease

KK Bence, MJ Birnbaum - Molecular metabolism, 2021 - Elsevier
Background The incidence of non-alcoholic fatty liver disease (NAFLD) is rapidly increasing
worldwide parallel to the global obesity epidemic. NAFLD encompasses a range of liver …

[HTML][HTML] Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From “two hit theory” to “multiple hit model”

YL Fang, H Chen, CL Wang, L Liang - World journal of …, 2018 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) has become the dominant form of chronic liver
disease in children and adolescents with the increasing prevalence of obesity worldwide …

Targeting autophagy in obesity: from pathophysiology to management

Y Zhang, JR Sowers, J Ren - Nature Reviews Endocrinology, 2018 - nature.com
Obesity poses a severe threat to human health, including the increased prevalence of
hypertension, insulin resistance, diabetes mellitus, cancer, inflammation, sleep apnoea and …

Effects of dietary fructose restriction on liver fat, de novo lipogenesis, and insulin kinetics in children with obesity

JM Schwarz, SM Noworolski, A Erkin-Cakmak, NJ Korn… - Gastroenterology, 2017 - Elsevier
Background & Aims Consumption of sugar is associated with obesity, type 2 diabetes
mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. The conversion of …

[HTML][HTML] Mitophagy and mitochondrial dynamics in type 2 diabetes mellitus treatment

Z Shan, WH Fa, CR Tian, CS Yuan, N Jie - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
The prevalence of type 2 diabetes is associated with inflammatory bowels diseases,
nonalcoholic steatohepatitis and even a spectrum of cancer such as colon cancer and liver …