Herpes simplex virus evasion of early host antiviral responses
EI Tognarelli, TF Palomino, N Corrales… - Frontiers in cellular …, 2019 - frontiersin.org
Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …
thousands of years and are present at a high prevalence in the population worldwide. HSV …
Pathobiology and treatment of viral keratitis
Keratitis is one of the most prevalent ocular diseases manifested by partial or total loss of
vision. Amongst infectious (viz., microbes including bacteria, fungi, amebae, and viruses) …
vision. Amongst infectious (viz., microbes including bacteria, fungi, amebae, and viruses) …
The Role of LAT in Increased CD8+ T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1
Herpes simplex virus (HSV) infection is a classic example of latent viral infection in humans
and experimental animal models. The HSV-1 latency-associated transcript (LAT) plays a …
and experimental animal models. The HSV-1 latency-associated transcript (LAT) plays a …
Roles of M1 and M2 macrophages in herpes simplex virus 1 infectivity
Macrophages are the predominant infiltrate in the corneas of mice that have been ocularly
infected with herpes simplex virus 1 (HSV-1). However, very little is known about the relative …
infected with herpes simplex virus 1 (HSV-1). However, very little is known about the relative …
Herpes simplex virus 1 ICP22 suppresses CD80 expression by murine dendritic cells
H Matundan, H Ghiasi - Journal of virology, 2019 - Am Soc Microbiol
Herpes simplex virus type 1 (HSV-1) has the ability to delay its clearance from the eye
during ocular infection. Here, we show that ocular infection of mice with HSV-1 suppressed …
during ocular infection. Here, we show that ocular infection of mice with HSV-1 suppressed …
Level of Herpes Simplex Virus Type 1 Latency Correlates with Severity of Corneal Scarring and Exhaustion of CD8+ T Cells in Trigeminal Ganglia of Latently Infected …
KR Mott, CJ Bresee, SJ Allen, L BenMohamed… - Journal of …, 2009 - Am Soc Microbiol
ABSTRACT A hallmark of infection with herpes simplex virus type 1 (HSV-1) is the
establishment of latency in ganglia of the infected individual. During the life of the latently …
establishment of latency in ganglia of the infected individual. During the life of the latently …
Crosstalk between epithelial cells, neurons and immune mediators in HSV-1 skin infection
Herpes simplex virus type 1 (HSV-1) infection is highly prevalent in humans, with
approximately two-thirds of the world population living with this virus. However, only a …
approximately two-thirds of the world population living with this virus. However, only a …
Stacking the odds: Multiple sites for HSV-1 latency
S Wang, X Song, A Rajewski, C Santiskulvong… - Science …, 2023 - science.org
A hallmark of herpes simplex virus (HSV) infection is the establishment of latent virus in
peripheral sensory ganglia of the latently infected host. We and others originally reported …
peripheral sensory ganglia of the latently infected host. We and others originally reported …
CD11c+ CD8α+ dendritic cells promote protective immunity to respiratory infection with Bordetella pertussis
Abstract CD11c+ CD8α+ and CD103+ dendritic cells (DC) have been shown to promote
regulatory T cell responses and mediate tolerance in the gastrointestinal tract. These cells …
regulatory T cell responses and mediate tolerance in the gastrointestinal tract. These cells …
CD8+ T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1
Based on an explant reactivation model, it has been proposed that CD8+ T cells maintain
latency in trigeminal ganglia (TG) of mice latently infected with herpes simplex virus 1 (HSV …
latency in trigeminal ganglia (TG) of mice latently infected with herpes simplex virus 1 (HSV …