Mammalian aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that
belongs to the basic helix–loop–helix (bHLH)–PAS family of transcription factors, which are …

Inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis are
characterized by uncontrolled activation of intestinal immune cells in a genetically …

Inflammatory bowel disease (IBD) is an inflammatory disease of the gastrointestinal tract, the
incidence of which has rapidly increased worldwide, especially in developing and Western …

Inter-individual human variability, driven by various genetic and environmental factors,
complicates the ability to develop effective population-based early disease detection …

Inflammatory bowel disease (IBD) refers to a gamut of disorders that are characterized by
chronic intestinal inflammation, including ulcerative colitis (UC) and Crohn's disease (CD) …

Ulcerative colitis (UC) is one of types of inflammatory bowel disease with high recurrence.
Recent studies have highlighted that microbial dysbiosis as well as abnormal gut immunity …

Background: Radix Sophorae flavescentis (Kushen), a Chinese herb, is widely used in the
treatment of ulcerative colitis (UC) with damp-heat accumulation syndrome (DHAS) …

Neutrophils migrate rapidly to damaged tissue and play critical roles in host defense and
tissue homeostasis. Here we investigated the mechanisms whereby neutrophils participate …

Background Ferroptosis, a type of programmed cell death triggered by oxidative stress, was
suspected to play a role in ulcerative colitis. Indigo naturalis is highly effective against …

A reduction in intestinal barrier function is currently believed to play an important role in
pathogenesis of many diseases, as it facilitates passage of injurious factors such as …