[HTML][HTML] Updates on global epidemiology, risk and prognostic factors of gastric cancer

WJ Yang, HP Zhao, Y Yu, JH Wang, L Guo… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Gastric cancer (GC) is defined as the primary epithelial malignancy derived from the
stomach, and it is a complicated and heterogeneous disease with multiple risk factors …

Lymph node metastasis in cancer progression: molecular mechanisms, clinical significance and therapeutic interventions

H Ji, C Hu, X Yang, Y Liu, G Ji, S Ge, X Wang… - … and Targeted Therapy, 2023 - nature.com
Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune
modulation, and secondary dissemination to distant sites through a series of mechanisms …

Emerging roles of circular RNAs in gastric cancer metastasis and drug resistance

X Wang, J Zhang, G Cao, J Hua, G Shan… - Journal of Experimental & …, 2022 - Springer
Gastric cancer (GC) is an aggressive malignancy with a high mortality rate and poor
prognosis, primarily caused by metastatic lesions. Improved understanding of GC metastasis …

Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway

G Chen, H Zhang, H Sun, X Ding, G Liu, F Yang… - Apoptosis, 2023 - Springer
Gastric cancer (GC) is the most common malignant tumor of digestive system. Bufalin
extracted from Venenum Bufonis is one of the most effective anticancer monomers, which …

CircNFATC3 promotes the proliferation of gastric cancer through binding to IGF2BP3 and restricting its ubiquitination to enhance CCND1 mRNA stability

F Yang, Q Ma, B Huang, X Wang, X Pan, T Yu… - Journal of Translational …, 2023 - Springer
Background Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) is an RNA
binding protein with multiple roles in regulation of gene expression at the post …

Hijacking and rewiring of host CircRNA/miRNA/mRNA competitive endogenous RNA (ceRNA) regulatory networks by oncoviruses during development of viral …

MJ Kamali, M Salehi, M Mostafavi… - Reviews in medical …, 2024 - Wiley Online Library
A significant portion of human cancers are caused by oncoviruses (12%–25%). Oncoviruses
employ various strategies to promote their replication and induce tumourigenesis in host …

Extracellular vesicles in gastric cancer: role of exosomal lncRNA and microRNA as diagnostic and therapeutic targets

C Jiang, J Zhang, W Wang, Z Shan, F Sun… - Frontiers in …, 2023 - frontiersin.org
Extracellular vesicles (EVs), including exosomes, play a crucial role in intercellular
communication and have emerged as important mediators in the development and …

Quercetin induces ferroptosis in gastric cancer cells by targeting SLC1A5 and regulating the p-Camk2/p-DRP1 and NRF2/GPX4 Axes

L Ding, S Dang, M Sun, D Zhou, Y Sun, E Li… - Free Radical Biology …, 2024 - Elsevier
Quercetin (Quer) is a natural flavonoid known for its inhibitory effects against various
cancers. However, the mechanism by which Quer inhibits gastric cancer (GC) has not yet …

Expression profiles of m6A RNA methylation regulators, PD-L1 and immune infiltrates in gastric cancer

Z Xu, Q Chen, L Shu, C Zhang, W Liu, P Wang - Frontiers in oncology, 2022 - frontiersin.org
Gastric cancer is the fourth most frequent cancer and has a high death rate. Immunotherapy
represented by PD-1 has brought hope for the treatment of advanced gastric cancer …

Upregulation of LINC00501 by H3K27 acetylation facilitates gastric cancer metastasis through activating epithelial‐mesenchymal transition and angiogenesis

R Dou, L Han, C Yang, Y Fang, J Zheng… - Clinical and …, 2023 - Wiley Online Library
Background The molecular mechanism of the significant role of long noncoding RNAs
(lncRNAs) in the progression and metastasis of gastric cancer (GC) remains largely elusive …