The endocannabinoid system (ECS) is involved in various processes, including brain
plasticity, learning and memory, neuronal development, nociception, inflammation, appetite …

This narrative review aims to pinpoint mental and behavioral effects of starvation, which may
be triggered by hypoleptinemia and as such may be amenable to treatment with leptin …

Exercise exerts a wide range of beneficial effects for healthy physiology 1. However, the
mechanisms regulating an individual's motivation to engage in physical activity remain …

To examine the hypothesis that normalization of low circulating leptin levels in patients with
anorexia nervosa ameliorates hyperactivity, three seriously ill females with hyperactivity …

Anorexia nervosa (AN) is classically defined as a condition in which an abnormally low body
weight is associated with an intense fear of gaining weight and distorted cognitions …

Dysfunctional signaling in midbrain reward circuits perpetuates diseases characterized by
compulsive overconsumption of rewarding substances such as substance abuse, binge …

Objective The incidence of depression is significantly compounded by obesity. Obesity
arising from excessive intake of high-fat food provokes anxiodepressive behavior and elicits …

Many of the neurocircuits and hormones known to underlie the sensations of hunger and
satiety also substantially alter the activity of the dopaminergic reward system. Much interest …

Background Increased physical activity is a common feature of anorexia nervosa (AN).
Although high activity levels are associated with greater risk of developing AN, particularly …

Chronic overconsumption of animal fats causes a variety of health problems, including
diabetes mellitus and obesity. Underlying molecular mechanisms encompass leptin …