Hypoxia and Porphyromonas gingivalis-lipopolysaccharide synergistically induce NLRP3 inflammasome activation in human gingival fibroblasts

K Yang, S Xu, H Zhao, L Liu, X Lv, F Hu, L Wang… - International …, 2021 - Elsevier
Objective To investigate the effects of hypoxia and Porphyromonas gingivalis-
lipopolysaccharide (P. gingivalis-LPS) on activation of the NACHT leucine-rich repeat …

Serum Inflammatory Factor Profiles in the Pathogenesis of High‐Altitude Polycythemia and Mechanisms of Acclimation to High Altitudes

H Yi, Q Yu, D Zeng, Z Shen, J Li, L Zhu… - Mediators of …, 2021 - Wiley Online Library
High‐altitude polycythemia (HAPC) is a common aspect of chronic mountain sickness
(CMS) caused by hypoxia and is the main cause of other symptoms associated with CMS …

Apigenin reduces the Toll-like receptor-4-dependent activation of NF-κB by suppressing the Akt, mTOR, JNK, and p38-MAPK

A Kim, CS Lee - Naunyn-Schmiedeberg's Archives of Pharmacology, 2018 - Springer
Flavone apigenin has an anti-inflammatory effect. We assessed whether apigenin may
reduce the inflammatory mediator production, which is regulated by the Toll-like receptor-4 …

[HTML][HTML] Association of Polymorphism with Periodontitis and Salivary Levels of Hypoxia-Inducible Factor-1α

WA Kzar, RF Abbas - European Journal of Dentistry, 2024 - thieme-connect.com
Objective This investigation aims to investigate the association between HIF-1α genetic
polymorphism and periodontitis and examine and contrast the levels of HIF-1α present in the …

Клинико-микробиологическое обоснование применения фотодинамической терапии и шинирования зубов в комплексном лечении заболеваний пародонта

ТТ Малазония - 2018 - elibrary.ru
Цель: повышение эффективности комплексного лечения пациентов с хроническим
пародонтитом. Методы исследования: клинические (опрос, осмотр, определение …

Porphyromonas gingivalis lipopolysaccharide regulates ephrin/Eph signalling in human periodontal ligament fibroblasts

M Li, C Zhang, L Jin, K Matsuo… - Journal of Periodontal …, 2017 - Wiley Online Library
Objective EphrinA2‐EphA2 and ephrinB2‐EphB4 critically engage in bidirectional signalling
to modulate alveolar bone remodelling. The present study aimed to investigate the effects of …

Interactions between phenolic constituents of Scutellaria salviifolia and key targets associated with inflammation: network pharmacology, molecular docking analysis …

Z Dogan, VM Kutluay, Y Genc… - Journal of Biomolecular …, 2023 - Taylor & Francis
Abstract Scutellaria salviifolia Benth.(SS), an endemic plant for Turkey, is used for gastric
ailments as folk medicine. In this study, we aimed to uncover the underlying molecular …

Role of the hypoxia-inducible factor in periodontal inflammation

XX Wang, Y Chen, WK Leung - Hypoxia and Human Diseases, 2017 - books.google.com
Human periodontitis is a chronic inflammatory disease induced by opportunistic
Gramnegative anaerobic bacteria at the tooth-supporting apparatus. Within the …

[PDF][PDF] Корекція гіпоксії в комплексному лікуванні захворювань пародонта

ІА Воловик - 2018 - ir.librarynmu.com
22 – Охорона здоров’я Page 1 22 – Охорона здоров’я Page 2 2 АНОТАЦІЯ Воловик ІАКорекція
гіпоксії в комплексному лікуванні захворювань пародонта. – Кваліфікаційна наукова праця …

Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia

J Cai, J Liu, J Yan, X Lu, X Wang, S Li… - Journal of …, 2022 - Wiley Online Library
Abstract Objective Periodontal ligament cells (PDLCs) are critical for wound healing and
regenerative capacity of periodontal diseases. Within an inflammatory periodontal pocket, a …