Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals
Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although
recent advances in cell-based models, including human-induced pluripotent stem cell …
recent advances in cell-based models, including human-induced pluripotent stem cell …
Characteristics of bisphenol cardiotoxicity: impaired excitability, contractility, and relaxation
BL Cooper, NG Posnack - Cardiovascular toxicology, 2022 - Springer
Bisphenol a (BPA) is a high production volume chemical that is frequently used to
manufacture epoxy resins and polycarbonate plastics. BPA-containing products are now …
manufacture epoxy resins and polycarbonate plastics. BPA-containing products are now …
High resolution optical mapping of cardiac electrophysiology in pre-clinical models
C O'Shea, J Winter, SN Kabir, M O'Reilly, SP Wells… - Scientific Data, 2022 - nature.com
Optical mapping of animal models is a widely used technique in pre-clinical cardiac
research. It has several advantages over other methods, including higher spatial resolution …
research. It has several advantages over other methods, including higher spatial resolution …
The effect of sex and age on ex vivo cardiac electrophysiology: insight from a guinea pig model
KT Haq, BL Cooper, F Berk… - American Journal of …, 2023 - journals.physiology.org
Highlighting the importance of sex as a biological variable, we recently reported sex
differences in guinea pig in vivo electrocardiogram (ECG) measurements. However …
differences in guinea pig in vivo electrocardiogram (ECG) measurements. However …
Diversity of cells and signals in the cardiovascular system
This white paper is the outcome of the seventh UC Davis Cardiovascular Research
Symposium on Systems Approach to Understanding Cardiovascular Disease and …
Symposium on Systems Approach to Understanding Cardiovascular Disease and …
Comparative cardiotoxicity assessment of bisphenol chemicals and estradiol using human induced pluripotent stem cell-derived cardiomyocytes
Bisphenol A (BPA) is commonly used to manufacture consumer and medical-grade plastics.
Due to health concerns, BPA substitutes are being incorporated—including bisphenol S …
Due to health concerns, BPA substitutes are being incorporated—including bisphenol S …
Evidence for the cardiodepressive effects of the plasticizer di-2-ethylhexyl phthalate
Abstract Di-2-ethylhexyl phthalate (DEHP) is commonly used in the manufacturing of plastic
materials, including intravenous bags, blood storage bags, and medical-grade tubing. DEHP …
materials, including intravenous bags, blood storage bags, and medical-grade tubing. DEHP …
[HTML][HTML] Multifactorial approaches to enhance maturation of human iPSC-derived cardiomyocytes
K Kistamás, A Müller, S Muenthaisong… - Journal of Molecular …, 2023 - Elsevier
Cardiovascular diseases are the leading cause of death worldwide. Several strategies–
small molecules, gene therapy, surgeries, cardiac rehabilitation–have been developed to …
small molecules, gene therapy, surgeries, cardiac rehabilitation–have been developed to …
[HTML][HTML] KairoSight-3.0: A validated optical mapping software to characterize cardiac electrophysiology, excitation-contraction coupling, and alternans
Background Cardiac optical mapping is an imaging technique that measures fluorescent
signals across a cardiac preparation. Dual optical imaging of voltage-sensitive and calcium …
signals across a cardiac preparation. Dual optical imaging of voltage-sensitive and calcium …
Demographic and methodological heterogeneity in electrocardiogram signals from guinea pigs
Electrocardiograms (ECG) are universally used to measure the electrical activity of the heart;
however, variations in recording techniques and/or subject demographics can affect ECG …
however, variations in recording techniques and/or subject demographics can affect ECG …