HIV-1 integrase inhibitors: a comparative review of efficacy and safety
KK Scarsi, JP Havens, AT Podany, SN Avedissian… - Drugs, 2020 - Springer
The newest class of antiretrovirals for all persons living with HIV are the integrase strand
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …
[PDF][PDF] Neuropsychiatric adverse events with dolutegravir and other integrase strand transfer inhibitors.
C Hoffmann, JM Llibre - AIDS reviews, 2019 - academia.edu
Neuropsychiatric adverse events (NPAEs) observed with the integrase strand transfer
inhibitor (INSTI) dolutegravir (DTG) are usually mild to moderate. The most prevalent …
inhibitor (INSTI) dolutegravir (DTG) are usually mild to moderate. The most prevalent …
Integrase inhibitors: after 10 years of experience, is the best yet to come?
The era of the integrase strand transfer inhibitors (INSTI s) for the treatment of human
immunodeficiency virus (HIV) infection began with raltegravir in 2007. Since that time …
immunodeficiency virus (HIV) infection began with raltegravir in 2007. Since that time …
Comparative clinical pharmacokinetics and pharmacodynamics of HIV-1 integrase strand transfer inhibitors: an updated review
Abstract Bictegravir, cabotegravir, dolutegravir, elvitegravir, and raltegravir are members of
the latest class of antiretrovirals available to treat human immunodeficiency virus (HIV) …
the latest class of antiretrovirals available to treat human immunodeficiency virus (HIV) …
Plasma Human Immunodeficiency Virus 1 RNA and CD4+ T-Cell Counts Are Determinants of Virological Nonsuppression Outcomes With Initial Integrase Inhibitor …
H Álvarez, A Mocroft, L Ryom… - Clinical Infectious …, 2023 - academic.oup.com
Background There are conflicting data regarding baseline determinants of virological
nonsuppression outcomes in persons with human immunodeficiency virus (HIV) starting …
nonsuppression outcomes in persons with human immunodeficiency virus (HIV) starting …
[HTML][HTML] A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection
AV Zhao, RD Crutchley, RC Guduru, K Ton, T Lam… - Retrovirology, 2022 - Springer
Integrase strand transfer inhibitors (INSTIs) have improved the treatment of human
immunodeficiency virus (HIV). There are currently four approved for use in treatment-naïve …
immunodeficiency virus (HIV). There are currently four approved for use in treatment-naïve …
Contribution of low CD4 cell counts and high human immunodeficiency virus (HIV) viral load to the efficacy of preferred first-line antiretroviral regimens for treating HIV …
JA Perez-Molina, C Crespillo-Andújar… - Clinical Infectious …, 2023 - academic.oup.com
We assessed whether low CD4 count and high viral load (VL) affect the response to
currently preferred ART. We performed a systematic review of randomized, controlled …
currently preferred ART. We performed a systematic review of randomized, controlled …
Plasma HIV-1 RNA and CD4⁺ T-cell counts are determinants of virological non-suppression outcomes with initial integrase inhibitor-based regimens: A prospective …
H Álvarez, A Mocroft, L Ryom… - Clinical Infectious …, 2023 - discovery.ucl.ac.uk
BACKGROUND: There are conflicting data regarding baseline determinants of virological
non-suppression outcomes in persons with HIV who initiate antiretroviral treatment (ART) …
non-suppression outcomes in persons with HIV who initiate antiretroviral treatment (ART) …
Integrase inhibitors: current protagonists in antiretroviral therapy
Since HIV was identified as the etiological agent of AIDS, there have been significant
advances in antiretroviral therapy (ART) that has reduced morbidity/mortality. Still, the viral …
advances in antiretroviral therapy (ART) that has reduced morbidity/mortality. Still, the viral …
[PDF][PDF] Dolutegravir neuropsychiatric adverse events: specific drug effect or class effect
JC Yombi - AIDS Rev, 2018 - dial.uclouvain.be
Integrase strand transfer inhibitors (INSTIs) are a newer class of antiretroviral treatment for
HIV-infected patient. INSTIs currently available for use are raltegravir, elvitegravir …
HIV-infected patient. INSTIs currently available for use are raltegravir, elvitegravir …