[HTML][HTML] The therapeutic potential of nanobodies

I Jovčevska, S Muyldermans - BioDrugs, 2020 - Springer
Today, bio-medical efforts are entering the subcellular level, which is witnessed with the fast-
developing fields of nanomedicine, nanodiagnostics and nanotherapy in conjunction with …

[HTML][HTML] Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

[HTML][HTML] Emerging applications of nanotechnology in healthcare systems: Grand challenges and perspectives

S Anjum, S Ishaque, H Fatima, W Farooq, C Hano… - Pharmaceuticals, 2021 - mdpi.com
Healthcare, as a basic human right, has often become the focus of the development of
innovative technologies. Technological progress has significantly contributed to the …

Nanomaterial-based blood-brain-barrier (BBB) crossing strategies

J Xie, Z Shen, Y Anraku, K Kataoka, X Chen - Biomaterials, 2019 - Elsevier
Increasing attention has been paid to the diseases of central nervous system (CNS). The
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to …

Crossing the blood-brain barrier with nanoparticles

Y Zhou, Z Peng, ES Seven, RM Leblanc - Journal of controlled release, 2018 - Elsevier
The blood-brain barrier (BBB) is one of the most essential protection mechanisms in the
central nervous system (CNS). It selectively allows individual molecules such as small lipid …

Current challenges and opportunities in treating glioblastoma

A Shergalis, A Bankhead, U Luesakul… - Pharmacological …, 2018 - ASPET
Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …

[HTML][HTML] Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

C Saraiva, C Praça, R Ferreira, T Santos… - Journal of controlled …, 2016 - Elsevier
The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …

Gold nanostructures: synthesis, properties, and neurological applications

I Zare, MT Yaraki, G Speranza, AH Najafabadi… - Chemical society …, 2022 - pubs.rsc.org
Recent advances in technology are expected to increase our current understanding of
neuroscience. Nanotechnology and nanomaterials can alter and control neural functionality …

Gold nanoparticles (GNPs) in biomedical and clinical applications: A review

MI Anik, N Mahmud, A Al Masud, M Hasan - Nano Select, 2022 - Wiley Online Library
Gold nanoparticles (GNPs) have been extensively used in various applications ranging from
environmental detection to biomedical applications. Due to their unique characteristics such …

Inorganic nano-drug delivery systems for crossing the blood–brain barrier: Advances and challenges

Q Tan, S Zhao, T Xu, Q Wang, M Zhang, L Yan… - Coordination Chemistry …, 2023 - Elsevier
The blood–brain barrier (BBB) exists between plasma and brain tissue. It comprises a
capillary wall and glial cells and prevents external substances, including therapeutic agents …