The process of spermatogenesis in Drosophila melanogaster provides a powerful model
system to probe a variety of developmental and cell biological questions, such as the …

In all animals, germline cells differentiate in intimate contact with somatic cells and
interactions between germline and soma are particularly important for germline …

Dosage compensation equalizes X-linked expression between XY males and XX females. In
male fruit flies, expression levels of the X-chromosome are increased approximately two-fold …

Non-obstructive azoospermia (NOA) is a complex and severe condition whose etiology
remains largely unknown. In a genome-wide association study (GWAS) of NOA in Chinese …

In regenerative tissues, one of the strategies to protect stem cells from genetic aberrations,
potentially caused by frequent cell division, is to transiently expand the stem cell daughters …

Background Rapid evolution is a hallmark of reproductive genetic systems and arises
through the combined processes of sequence divergence, gene gain and loss, and changes …

REPRODUCTION Page 1 REPRODUCTION RESEARCH Characterization of spermatogonial
markers in the mature testis of the dogfish (Scyliorhinus canicula L.) Adrien Bosseboeuf1,2,3,4 …

One fundamental property of a stem cell niche is the exchange of molecular signals between
its component cells. Niche models, such as the Drosophila melanogaster testis, have been …

Stem cells (SCs) undergo asymmetric division, producing transit-amplifying cells (TACs) with
increased proliferative potential that move into tissues and ultimately differentiate into a …

Gonadal soma–derived factor (gsdf) has been demonstrated to be essential for testicular
differentiation in medaka (Oryzias latipes). To understand the protein dynamics of Gsdf in …