Numerical study on electromechanics in cartilage tissue with respect to its electrical properties

AR Farooqi, R Bader, U van Rienen - Tissue Engineering Part B …, 2019 - liebertpub.com
Hyaline cartilage undergoes many substantial age-related physiochemical and
biomechanical changes that reduce its ability to overcome the effects of mechanical stress …

基于机器学习软骨细胞的时间依赖性力学行为及本构参数反演

魏新宇, 桑建兵, 张睿琳, 王静远, 刘宝友 - 力学学报, 2022 - lxxb.cstam.org.cn
探究软骨细胞机械负载下的力学特性对于理解软骨细胞的正常和病理状态以及骨性关节炎的
病因至关重要. 基于软骨细胞有限元计算模型的力学响应与其本构参数之间的高度复杂非线性 …

Investigation of cell-substrate adhesion properties of living chondrocyte by measuring adhesive shear force and detachment using AFM and inverse FEA

TD Nguyen, YT Gu - Scientific reports, 2016 - nature.com
It is well-known that cell adhesion is important in many biological processes such as cell
migration and proliferation. A better understanding of the cell adhesion process will shed …

Effect of substrate stiffness on mechanical coupling and force propagation at the infarct boundary

DT Nguyen, N Nagarajan, P Zorlutuna - Biophysical journal, 2018 - cell.com
Heterogeneous intercellular coupling plays a significant role in mechanical and electrical
signal transmission in the heart. Although many studies have investigated the electrical …

A combined experimental atomic force microscopy-based nanoindentation and computational modeling approach to unravel the key contributors to the time …

C Florea, P Tanska, ME Mononen, C Qu… - … and modeling in …, 2017 - Springer
Cellular responses to mechanical stimuli are influenced by the mechanical properties of
cells and the surrounding tissue matrix. Cells exhibit viscoelastic behavior in response to an …

Time-dependent mechanical behavior and constitutive parameter identification of chondrocytes based on machine learning

W Xinyu, S Jianbing, Z Ruilin, W Jingyuan… - Chinese Journal of …, 2022 - lxxb.cstam.org.cn
Research on the mechanical properties of chondrocytes under mechanical loading is crucial
to understanding their normal and pathological states of chondrocytes and the etiology of …

Exploration of mechanisms underlying the strain-rate-dependent mechanical property of single chondrocytes

TD Nguyen, YT Gu - Applied Physics Letters, 2014 - pubs.aip.org
Based on the characterization by Atomic Force Microscopy, we report that the mechanical
property of single chondrocytes has dependency on the strain-rates. By comparing the …

Determination of strain-rate-dependent mechanical behavior of living and fixed osteocytes and chondrocytes using atomic force microscopy and inverse finite element …

TD Nguyen, YT Gu - Journal of biomechanical …, 2014 - asmedigitalcollection.asme.org
The aim of this paper is to determine the strain-rate-dependent mechanical behavior of living
and fixed osteocytes and chondrocytes, in vitro. First, atomic force microscopy (AFM) was …

Microscale consolidation analysis of relaxation behavior of single living chondrocytes subjected to varying strain-rates

TD Nguyen, A Oloyede, S Singh, YT Gu - Journal of the Mechanical …, 2015 - Elsevier
Besides the elastic stiffness, the relaxation behavior of single living cells is also of interest of
various researchers when studying cell mechanics. It is hypothesized that the relaxation …

Stress relaxation analysis of single chondrocytes using porohyperelastic model based on AFM experiments

TD Nguyen, A Oloyede, Y Gu - Theoretical and Applied Mechanics Letters, 2014 - Elsevier
Based on atomic force microscopytechnique, we found that the chondrocytes exhibits stress
relaxation behavior. We explored the mechanism of this stress relaxation behavior and …