Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …

Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …

Traditionally studies of brain function have focused on task-evoked responses. By their very
nature such experiments tacitly encourage a reflexive view of brain function. While such an …

Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …

Traditionally studies of brain function have focused on task-evoked responses. By their very
nature, such experiments tacitly encourage a reflexive view of brain function. Although such …

Functional brain imaging with positron emission tomography and magnetic resonance
imaging has been used extensively to map regional changes in brain activity. The signal …

Neurons are metabolically handicapped in the sense that they are not able to perform de
novo synthesis of neurotransmitter glutamate and γ‐aminobutyric acid (GABA) from glucose …

The continuous need for ion gradient restoration across the cell membrane, a prerequisite
for synaptic transmission and conduction, is believed to be a major factor for brain's high …

Gamma oscillations (~ 30 to 100 Hz) provide a fundamental mechanism of information
processing during sensory perception, motor behavior, and memory formation by …

Astrocytic energy demand is stimulated by K+ and glutamate uptake, signaling processes,
responses to neurotransmitters, Ca2+ fluxes, and filopodial motility. Astrocytes derive energy …