Chronic liver disease (CLD) is a growing health concern which accounts for two million
deaths per year. Obesity, alcohol overconsumption, and progressive cholestasis are …

The scavenger receptor superfamily represents a highly diverse collection of evolutionarily-
conserved receptors which are known to play key roles in host homeostasis, the most …

The efficacy of immune checkpoint inhibitors (ICI) in the treatment of hepatocellular
carcinoma (HCC) remains limited, highlighting the need for further investigation into the …

Although immunotherapeutic strategies such as immune checkpoint inhibitors (ICIs) have
gained promising advances, their limited efficacy and significant toxicity remain great …

Tumor-infiltrating immune cells and their crosstalk with cancer cells in the tumor
microenvironment (TME) play a crucial role in shaping tumor progression and response to …

摘要肝癌在全球范围内是第六大最常见的癌症类型, 同时也是导致癌症死亡的第三大原因.
约有30% 的患者在诊断时处于肝癌早期阶段, 此时可以通过包括肝部分切除术和肝移植在内的 …

Chronic liver disease (CLD) is a growing health concern which accounts for two million
deaths per year. Obesity, alcohol overconsumption, and progressive cholestasis are …

Background Immune-checkpoint blockade (ICB) therapies by antibodies against
programmed death 1 (PD1)/PD1 ligand 1 (PD-L1) axis have revolutionized the treatment …

Liver disease is one of the leading causes of mortality in the United Kingdom, with cirrhosis
becoming one of the top three causes of premature death in people aged 30 to 60 years. 1 …