Adipose-derived mesenchymal stem cells therapy as a new treatment option for diabetes mellitus

A Mikłosz, A Chabowski - The Journal of Clinical Endocrinology …, 2023 - academic.oup.com
The worldwide increase in the prevalence of diabetes mellitus has raised the demand for
new therapeutic strategies targeting diabetic symptoms and its chronic complications …

Towards halal pharmaceutical: Exploring alternatives to animal-based ingredients

Y Herdiana, FF Sofian, S Shamsuddin, T Rusdiana - Heliyon, 2024 - cell.com
Halal is a crucial concept for Muslim consumers regarding consumed products, including
pharmaceutical ingredients, which are essential in modern medicine. To address the issue …

Insulin-producing cells from bone marrow stem cells versus injectable insulin for the treatment of rats with type I diabetes

SH Azeez, SN Jafar, Z Aziziaram, L Fang… - Cellular, Molecular …, 2021 - cmbr-journal.com
Recently, stem cells have been considered renewable cell sources in the treatment of
diabetes and the development of insulin-producing cells. In this regard, the current study …

Comparison of therapeutic effects of mesenchymal stem cells from umbilical cord and bone marrow in the treatment of type 1 diabetes

W Zhang, Q Ling, B Wang, K Wang, J Pang… - Stem cell research & …, 2022 - Springer
Background The therapeutic potential of mesenchymal stem cells (MSCs) in type 1 diabetes
(T1D) has been demonstrated in both preclinical and clinical studies. MSCs that have been …

Bone marrow mesenchymal stromal cells for diabetes therapy: touch, fuse, and fix?

Z Azizi, R Abbaszadeh, R Sahebnasagh… - Stem Cell Research & …, 2022 - Springer
Bone marrow mesenchymal stromal cells (BM-MSCs) have anti-inflammatory and pro-
survival properties. Naturally, they do not express human leukocyte antigen class II surface …

Current status of stem cell therapy for type 1 diabetes: a critique and a prospective consideration

MA Ghoneim, MM Gabr, SM El-Halawani… - Stem Cell Research & …, 2024 - Springer
Over the past decade, there had been progress in the development of cell therapy for insulin-
dependent diabetes. Nevertheless, important hurdles that need to be overcome still remain …

Exploring cutting-edge approaches in diabetes care: from nanotechnology to personalized therapeutics

GF Asaad, AS Doghish, AA Rashad… - Naunyn-Schmiedeberg's …, 2024 - Springer
Diabetes mellitus (DM) is a persistent condition characterized by high levels of glucose in
the blood due to irregularities in the secretion of insulin, its action, or both. The disease was …

A Supportive Role of Mesenchymal Stem Cells on Insulin-Producing Langerhans Islets with a Specific Emphasis on The Secretome

RV Sionov, R Ahdut-HaCohen - Biomedicines, 2023 - mdpi.com
Type 1 Diabetes (T1D) is a chronic autoimmune disease characterized by a gradual
destruction of insulin-producing β-cells in the endocrine pancreas due to innate and specific …

Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice

MA Ghoneim, MM Gabr, AF Refaie… - Stem Cell Research & …, 2022 - Springer
Background The purpose of this study was to investigate allogenic immune responses
following the transplantation of insulin-producing cells (IPCs) differentiated from human …

[HTML][HTML] The Role of Mesenchymal Stem Cells in Modulating Adaptive Immune Responses in Multiple Sclerosis

S Dadfar, E Yazdanpanah, A Pazoki, MH Nemati… - Cells, 2024 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system,
leading to significant disability through neurodegeneration. Despite advances in the …