[HTML][HTML] Hepatitis B and renal disease

TM Chan - Current hepatitis reports, 2010 - Springer
Glomerulonephritis is an important extrahepatic manifestation of chronic hepatitis B virus
(HBV) infection. The uncommon occurrence, variability in renal histopathology, and …

[HTML][HTML] Ionizable liposomal siRNA therapeutics enables potent and persistent treatment of Hepatitis B

Y Huang, S Zheng, Z Guo… - Signal transduction and …, 2022 - nature.com
Small interfering RNA (siRNA) constitutes a promising therapeutic modality supporting the
potential functional cure of hepatitis B. A novel ionizable lipidoid nanoparticle (RBP131) and …

Chronic viral hepatitis and chronic kidney disease

EC Chacko, SK Surrun… - Postgraduate …, 2010 - academic.oup.com
Chronic kidney disease (CKD) has become a major public health problem worldwide over
the past few decades because of the increasing prevalence of hypertension, diabetes …

CRISPR/Cas9 produces anti-hepatitis B virus effect in hepatoma cells and transgenic mouse

W Zhu, K Xie, Y Xu, L Wang, K Chen, L Zhang, J Fang - Virus research, 2016 - Elsevier
Chronic infection of hepatitis B virus (HBV) is at risk of liver cirrhosis and hepatocellular
carcinoma and remains one of the major public health problems worldwide. It is a major …

Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection

X Tian, C Zhao, H Zhu, W She, J Zhang, J Liu… - Journal of …, 2010 - Am Soc Microbiol
Cyclophilin A (CypA), predominantly located intracellularly, is a multifunctional protein. We
previously reported decreased CypA levels in hepatocytes of transgenic mice expressing …

Expression of hepatitis B virus proteins in transgenic mice alters lipid metabolism and induces oxidative stress in the liver

F Yang, S Yan, Y He, F Wang, S Song, Y Guo… - Journal of …, 2008 - Elsevier
BACKGROUND/AIMS: Hepatitis B virus transgenic mice (HBV-Tg mice) have been widely
used as animal models in the study of pathogenesis and control of hepatitis B. It is important …

A human monoclonal antibody against small envelope protein of hepatitis B virus with potent neutralization effect

W Wang, L Sun, T Li, Y Ma, J Li, Y Liu, M Li, L Wang… - MAbs, 2016 - Taylor & Francis
Hepatitis B virus (HBV) produces large (L), middle (M), and small (S) envelope proteins,
alternatively referred to as hepatitis B surface antigen (HBsAg). Currently, yeast-derived S …

PD‐1/PDL 1 and CD 28/CD 80 pathways modulate natural killer T cell function to inhibit hepatitis B virus replication

XF Wang, Y Lei, M Chen, CB Chen… - Journal of Viral …, 2013 - Wiley Online Library
Summary α‐Galactosylceramide (α‐G al C er)‐activated natural killer T (NKT) cells have
antiviral properties against hepatitis B virus (HBV). However, α‐GalCer activation of NKT …

An altered pattern of liver apolipoprotein AI isoforms is implicated in male chronic hepatitis B progression

F Yang, Y Yin, F Wang, L Zhang… - Journal of proteome …, 2010 - ACS Publications
Chronic hepatitis B (CHB) appears to progress more rapidly in males than in females, and
CHB-related hepatic cirrhosis and hepatocellular carcinoma are predominately diseases …

Anti‐Hepatitis B Virus Effect and Possible Mechanism of Action of 3,4‐O‐Dicaffeoylquinic Acid In Vitro and In Vivo

YH Wu, BJ Hao, HC Cao, W Xu, YJ Li… - Evidence‐Based …, 2012 - Wiley Online Library
The anti‐hepatitis B activity of 3, 4‐O‐dicaffeoylquinic acid isolated from Laggera alata was
studied using the d‐galactosamine‐(d‐GalN‐) induced hepatocyte damage model, HepG2 …