SARS-CoV-2 infection during pregnancy and risk of preeclampsia: a systematic review and meta-analysis

A Conde-Agudelo, R Romero - American journal of obstetrics and …, 2022 - Elsevier
Objective To examine the relationship between SARS-CoV-2 infection during pregnancy
and the risk for preeclampsia. Data Sources MEDLINE, Embase, POPLINE, CINAHL …

[HTML][HTML] The influence of evolutionary history on human health and disease

ML Benton, A Abraham, AL LaBella, P Abbot… - Nature Reviews …, 2021 - nature.com
Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

[HTML][HTML] Human placenta and trophoblast development: key molecular mechanisms and model systems

M Knöfler, S Haider, L Saleh, J Pollheimer… - Cellular and Molecular …, 2019 - Springer
Abnormal placentation is considered as an underlying cause of various pregnancy
complications such as miscarriage, preeclampsia and intrauterine growth restriction, the …

Pre-eclampsia: pathophysiology and clinical implications

GJ Burton, CW Redman, JM Roberts, A Moffett - Bmj, 2019 - bmj.com
Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical
presentation is highly variable but hypertension and proteinuria are usually seen. These …

[HTML][HTML] Human placental development and function

T Cindrova-Davies, AN Sferruzzi-Perri - Seminars in cell & developmental …, 2022 - Elsevier
The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …

[HTML][HTML] Pathogenesis of preeclampsia and therapeutic approaches targeting the placenta

MK Jena, NR Sharma, M Petitt, D Maulik, NR Nayak - Biomolecules, 2020 - mdpi.com
Preeclampsia (PE) is a serious pregnancy complication, affecting about 5–7% of
pregnancies worldwide and is characterized by hypertension and damage to multiple …

Cellular immune responses in the pathophysiology of preeclampsia

D Miller, K Motomura, J Galaz… - Journal of Leukocyte …, 2022 - academic.oup.com
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta

G Meinhardt, S Haider, V Kunihs… - Proceedings of the …, 2020 - National Acad Sciences
Various pregnancy complications, such as severe forms of preeclampsia or intrauterine
growth restriction, are thought to arise from failures in the differentiation of human placental …

[HTML][HTML] Toward a new taxonomy of obstetrical disease: improved performance of maternal blood biomarkers for the great obstetrical syndromes when classified …

R Romero, E Jung, T Chaiworapongsa, O Erez… - American journal of …, 2022 - Elsevier
Background The major challenge for obstetrics is the prediction and prevention of the great
obstetrical syndromes. We propose that defining obstetrical diseases by the combination of …

[HTML][HTML] How ERAP1 and ERAP2 shape the peptidomes of disease-associated MHC-I proteins

JA López de Castro - Frontiers in Immunology, 2018 - frontiersin.org
Four inflammatory diseases are strongly associated with Major Histocompatibility Complex
class I (MHC-I) molecules: birdshot chorioretinopathy (HLA-A* 29: 02), ankylosing …