State-of-the-Art opinion article on ventilator-induced diaphragm dysfunction: update on diagnosis, clinical course, and future treatment options

J Spiesshoefer, A Kersten, J Enriquez Geppert… - Respiration, 2023 - karger.com
Evidence from both animal and human studies now supports the development of ventilator-
induced diaphragm dysfunction (VIDD) starting as early as 24 h after initiation of mechanical …

Deciphering the mechanisms underlying brain alterations and cognitive impairment in congenital myotonic dystrophy

T De Serres-Bérard, M Pierre, M Chahine… - Neurobiology of …, 2021 - Elsevier
Abstract Myotonic dystrophy type 1 (DM1) is a multisystemic and heterogeneous disorder
caused by the expansion of CTG repeats in the 3'UTR of the myotonic dystrophy protein …

Association of diaphragm thickness and echogenicity with age, sex, and body mass index in healthy subjects

JLM van Doorn, J Wijntjes, CGJ Saris… - Muscle & …, 2022 - Wiley Online Library
Abstract Introduction/Aims Diaphragm ultrasound is increasingly used in the diagnosis of
diaphragm dysfunction and to guide respiratory management in patients with neuromuscular …

Central nervous system involvement as outcome measure for clinical trials efficacy in myotonic dystrophy type 1

C Simoncini, G Spadoni, E Lai, L Santoni… - Frontiers in …, 2020 - frontiersin.org
Increasing evidences indicate that in Myotonic Dystrophy type 1 (DM1 or Steinert disease),
an autosomal dominant multisystem disorder caused by a (CTG) n expansion in DMPK gene …

Inspiratory muscle dysfunction and restrictive lung function impairment in congenital heart disease: Association with immune inflammatory response and exercise …

J Spiesshoefer, S Orwat, C Henke, HJ Kabitz… - International journal of …, 2020 - Elsevier
Background In adult patients with congenital heart disease (ACHD), both underlying disease
and lung restriction contribute to exercise intolerance. In ACHD the yet incompletely …

Hypoxia and hypoxia-inducible factor signaling in muscular dystrophies: cause and consequences

TH Nguyen, S Conotte, A Belayew… - International journal of …, 2021 - mdpi.com
Muscular dystrophies (MDs) are a group of inherited degenerative muscle disorders
characterized by a progressive skeletal muscle wasting. Respiratory impairments and …

Heart failure results in inspiratory muscle dysfunction irrespective of left ventricular ejection fraction

J Spiesshoefer, C Henke, HJ Kabitz, P Bengel, K Schütt… - Respiration, 2021 - karger.com
Background: Exercise intolerance in heart failure with reduced ejection fraction (HFrEF) or
heart failure with preserved ejection fraction (HFpEF) results from both cardiac dysfunction …

Respiratory muscle imaging by ultrasound and MRI in neuromuscular disorders

JLM van Doorn, F Pennati, HHG Hansen… - European …, 2021 - Eur Respiratory Soc
Respiratory muscle weakness is common in neuromuscular disorders (NMDs) and leads to
significant respiratory difficulties. Therefore, reliable and easy assessment of respiratory …

Differences in respiratory function, depressive symptoms and quality of life between patients with hereditary motor and sensory neuropathy and myotonic dystrophy …

N Lajlar, G Vidmar, M Moharić - International journal of …, 2024 - journals.lww.com
Hereditary motor and sensory neuropathy (HMSN) and myotonic dystrophy (MD) are chronic
neuromuscular diseases that cause progressive muscular impairment and impact patient's …

Muscle ultrasound in myopathies

A Vicino, D Veltsista, N van Alfen - Current Opinion in Neurology, 2024 - journals.lww.com
Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get new
issue alertsGet alerts Secondary Logo Journal Logo Advanced Search Toggle navigation …