[HTML][HTML] Review of hybrid PLGA nanoparticles: Future of smart drug delivery and theranostics medicine

J Ghitman, EI Biru, R Stan, H Iovu - Materials & Design, 2020 - Elsevier
The concept of PLGA-lipid hybrid nanoparticles arose as a motivation for developing drug
delivery systems with versatile physical and chemical properties, unequivocal therapeutic …

Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon

TP Brown, V Ganapathy - Pharmacology & therapeutics, 2020 - Elsevier
Reprogramming of biochemical pathways is a hallmark of cancer cells, and generation of
lactic acid from glucose/glutamine represents one of the consequences of such metabolic …

Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review

MH Elkomy, AA Ali, HM Eid - Journal of Controlled Release, 2022 - Elsevier
The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

Drug-loaded PEG-PLGA nanoparticles for cancer treatment

D Zhang, L Liu, J Wang, H Zhang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Nanoparticles based on single-component synthetic polymers, such as poly (lactic acid-co-
glycolic acid)(PLGA), have been extensively studied for antitumor drug delivery and …

Polymeric nanoparticles-siRNA as an emerging nano-polyplexes against ovarian cancer

U Rehman, N Parveen, A Sheikh… - Colloids and Surfaces B …, 2022 - Elsevier
Ovarian cancer (OC) is considered fifth-deadliest cancer globally responsible for high
mortality in women. As the conventional therapeutic and diagnostic approaches are …

Nanotechnology-based siRNA delivery strategies for treatment of triple negative breast cancer

R Chadar, P Kesharwani - International Journal of Pharmaceutics, 2021 - Elsevier
Triple negative breast cancer (TNBC) is a subtype of breast cancer characterized by
absence of estrogen (ER) receptor, progesterone (PR) receptor, and human epidermal …

Trends in smart drug delivery systems for targeting cancer cells

S Kandula, PK Singh, GA Kaur, A Tiwari - Materials Science and …, 2023 - Elsevier
Cancer is a worldwide health issue, and there is still a considerable demand for innovative
treatments. Smart drug delivery systems have gained popularity to improve the effectiveness …

[HTML][HTML] Evaluation of curcumin loaded chitosan/PEG blended PLGA nanoparticles for effective treatment of pancreatic cancer

G Arya, M Das, SK Sahoo - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Pancreatic cancer is considered as one of the most lethal type of cancer with a poor 5-year
survival rate. Cancer metastasis represents one of the primary cause which limits therapy …

Targeted therapy of breast tumor by PLGA-based nanostructures: The versatile function in doxorubicin delivery

TS Dongsar, TT Dongsar, N Molugulu… - Environmental …, 2023 - Elsevier
Breast carcinoma is a molecularly diverse illness, and it is among the most prominent and
often reported malignancies in female across the globe. Surgical intervention …

Recent advances of dendrimers as multifunctional nano-carriers to combat breast cancer

SK Dubey, M Kali, S Hejmady, RN Saha… - European Journal of …, 2021 - Elsevier
Breast Cancer (BC) is a highly heterogeneous malignant carcinoma that is the most
frequently occurring cancer in women. The major types of BC are luminal A, basal-like …