Millions of people worldwide lie at the risk of parasitic protozoic infections that kill over a
million people each year. The rising inefficacy of conventional therapeutics to combat these …

Entamoeba histolytica, the causative agent of human amoebiasis, exhibits a continuous
membrane remodelling to exert its virulence properties. During this dynamic process, the …

The chapter is an effort to provide in-depth knowledge about the basic principles involved in
isothermal titration calorimetry (ITC) technique along with practical considerations. It is an …

In humans and Drosophila melanogaster, the functional convergence of the endosomal
sorting complex required for transport (ESCRT) machinery that is in charge of selecting …

The retromer is a cellular structure that recruits and recycles proteins inside the cell. In
mammalian and yeast, the retromer components have been widely studied, but very little in …

Phosphatidylinositol phosphates (PIPs) function as important second messengers in many
cellular events. In the human intestinal protist Entamoeba histolytica, where phagocytosis …

Protein-protein interactions play important roles for a variety of cell functions, often involving
metal ions; in fact, metal-ion binding mediates and regulates the activity of a wide range of …

Amoebiasis is a parasitic infectious disease caused by the enteric protozoan Entamoeba
histolytica, a leading basis of deaths accounted to parasites, succeeding malaria and …

The retromer is a highly conserved eukaryotic complex formed by the cargo selective
complex (CSC) and the sorting nexin (SNX) dimer subcomplexes. Its function is protein …

By their active movement and voraux phagocytosis, the trophozoites of Entamoeba
histolytica constitute an excellent system to investigate the dynamics of the Endosomal …