Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …

Melatonin is remarkably functionally diverse with actions as a free radical scavenger and
antioxidant, circadian rhythm regulator, anti‐inflammatory and immunoregulating molecule …

During recent years, an increasing percentage of male infertility has to be attributed to an
array of environmental, health and lifestyle factors. Male infertility is likely to be affected by …

Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …

Diabetic retinopathy (DR), a microvascular complication of diabetes mellitus (DM), remains
as one of the major causes of vision loss worldwide. The release of pro-inflammatory …

The discovery of melatonin and its derivatives as antioxidants has stimulated a very large
number of studies which have, virtually uniformly, documented the ability of these molecules …

This review aims at describing the beneficial properties of melatonin related to its antioxidant
effects. Oxidative stress, ie, an imbalance between the production of reactive oxygen …

Melatonin is an uncommonly widely distributed molecule. It is found throughout the plant
and animal kingdoms, ie, perhaps in every living organism. Within vertebrate organisms …

Melatonin is the primary circadian output signal from the brain and is mainly synthesized in
pinealocytes. The rhythm and secretion of melatonin are under the control of an …

This review summarizes some of the recent findings concerning the long-held tenet that the
enzyme, N-acetyltransferase, which is involved in the production of N-acetylserotonin, the …