Intrinsic membrane permeability to small molecules

C Hannesschlaeger, A Horner, P Pohl - Chemical reviews, 2019 - ACS Publications
Spontaneous solute and solvent permeation through membranes is of vital importance to
human life, be it gas exchange in red blood cells, metabolite excretion, drug/toxin uptake, or …

Time-dependent diffusion MRI in cancer: tissue modeling and applications

O Reynaud - Frontiers in Physics, 2017 - frontiersin.org
In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been
recognized as a useful and sensitive surrogate for cell density, paving the way for non …

Determining the longitudinal relaxation time (T1) of blood at 3.0 Tesla

H Lu, C Clingman, X Golay… - Magnetic Resonance in …, 2004 - Wiley Online Library
It is important to determine the longitudinal relaxation time of blood for black blood imaging,
as well as for quantifying blood flow by arterial spin labeling (ASL). In this study a circulation …

Functional magnetic resonance imaging based on changes in vascular space occupancy

H Lu, X Golay, JJ Pekar… - Magnetic Resonance in …, 2003 - Wiley Online Library
During brain activation, local control of oxygen delivery is facilitated through microvascular
dilatation and constriction. A new functional MRI (fMRI) methodology is reported that is …

Calibration and validation of TRUST MRI for the estimation of cerebral blood oxygenation

H Lu, F Xu, K Grgac, P Liu, Q Qin… - Magnetic resonance in …, 2012 - Wiley Online Library
Abstract Recently, a T2‐Relaxation‐Under‐Spin‐Tagging (TRUST) MRI technique was
developed to quantitatively estimate blood oxygen saturation fraction (Y) via the …

Highlighting membrane protein structure and function: A celebration of the Protein Data Bank

F Li, PF Egea, AJ Vecchio, I Asial, M Gupta… - Journal of Biological …, 2021 - ASBMB
Biological membranes define the boundaries of cells and compartmentalize the chemical
and physical processes required for life. Many biological processes are carried out by …

Oxygenation and hematocrit dependence of transverse relaxation rates of blood at 3T

JM Zhao, CS Clingman, MJ Närväinen… - … in Medicine: An …, 2007 - Wiley Online Library
Abstract Knowledge of the transverse relaxation rates R2 and R of blood is relevant for
quantitative assessment of functional MRI (fMRI) results, including calibration of blood …

Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Measurement of tissue oxygen extraction ratios from venous blood T2: Increased precision and validation of principle

X Golay, MJ Silvennoinen, J Zhou… - … in Medicine: An …, 2001 - Wiley Online Library
It has recently been shown that parenchymal oxygen extraction ratios (OERs) can be
quantified using the absolute T2 of venous blood draining from this tissue (Oja et al., J Cereb …

The first discovered water channel protein, later called aquaporin 1: molecular characteristics, functions and medical implications

G Benga - Molecular aspects of medicine, 2012 - Elsevier
After a decade of work on the water permeability of red blood cells (RBC) Benga group in
Cluj-Napoca, Romania, discovered in 1985 the first water channel protein in the RBC …