Retinal electrophysiology in central nervous system disorders. A review of human and mouse studies

PA Constable, JKH Lim, DA Thompson - Frontiers in Neuroscience, 2023 - frontiersin.org
The retina and brain share similar neurochemistry and neurodevelopmental origins, with the
retina, often viewed as a “window to the brain.” With retinal measures of structure and …

Retina as a potential biomarker in schizophrenia spectrum disorders: a systematic review and meta-analysis of optical coherence tomography and electroretinography

H Komatsu, G Onoguchi, SM Silverstein, S Jerotic… - Molecular …, 2023 - nature.com
Introduction Abnormal findings on optical coherence tomography (OCT) and
electroretinography (ERG) have been reported in participants with schizophrenia spectrum …

Visual hallucinations in psychosis: the curious absence of the primary visual cortex

MM van Ommen, T van Laar, R Renken… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background and Hypothesis Approximately one-third of patients with a psychotic
disorder experience visual hallucinations (VH). While new, more targeted treatment options …

[HTML][HTML] Measures of retinal structure and function as biomarkers in neurology and psychiatry

SM Silverstein, DL Demmin, JB Schallek… - Biomarkers in …, 2020 - Elsevier
Investigators have increasingly turned to studying the retina as a window into brain structure
and function. In neuropsychiatric diseases, retinal anatomy as assessed by optical …

The phenomenology and neurobiology of visual distortions and hallucinations in schizophrenia: an update

SM Silverstein, A Lai - Frontiers in Psychiatry, 2021 - frontiersin.org
Schizophrenia is characterized by visual distortions in~ 60% of cases, and visual
hallucinations (VH) in~ 25–50% of cases, depending on the sample. These symptoms have …

Differentiation of the retinal morphology aging trajectories in schizophrenia and their associations with cognitive dysfunctions

A Domagała, L Domagała, N Kopiś-Posiej… - Frontiers in …, 2023 - frontiersin.org
Previous studies evaluating the morphology of the selected retinal layers in schizophrenia
showed abnormalities regarding macular thickness, retinal nerve fiber layer (RNLF), and …

Structural and functional retinal alterations in patients with paranoid schizophrenia

EBN Friedel, HT Hahn, S Maier, S Küchlin… - Translational …, 2022 - nature.com
Ophthalmological methods have increasingly raised the interest of neuropsychiatric
specialists. While the integrity of the retinal cell functions can be evaluated with the …

Evaluation of electroretinography (ERG) parameters as a biomarker for ADHD

MA Dubois, CA Pelletier, C Mérette, V Jomphe… - Progress in Neuro …, 2023 - Elsevier
Background The retina is recognized as an accessible part of the brain due to their common
embryonic origin. The electroretinogram (ERG) has proven to be a valuable tool for …

Visual hallucinations in psychiatric, neurologic, and ophthalmologic disease

KA Coerver, PS Subramanian - Current opinion in ophthalmology, 2020 - journals.lww.com
Visual hallucinations are common, and patients may not report them if specific inquiries are
not made. Presence or absence of hallucinations may be of diagnostic and therapeutic …

Altered central vision and amacrine cells dysfunction as marker of hypodopaminergic activity in treated patients with schizophrenia

F Bernardin, T Schwitzer, R Schwan… - Schizophrenia …, 2022 - Elsevier
Background Retinal dysfunction is widely documented in schizophrenia using flash (fERG)
and pattern electroretinograms (PERG), but the role of dopamine transmission has seldom …