Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Fibromyalgia (FM) is a syndrome that does not present a well-defined underlying organic
disease. FM is a condition which has been associated with diseases such as infections …

Central sensitization (CS) is defined as an increased nociceptive responsiveness due to
sensitization of neurons in the central nervous system, usually the result of prolonged …

Chronic pain is sustained, in part, through the intricate process of central sensitization (CS),
marked by maladaptive neuroplasticity and neuronal hyperexcitability within central pain …

This narrative review summarizes the current knowledge of the genetic and epigenetic
contributions to the development of fibromyalgia (FM). Although there is no single gene that …

Epigenomic modifications of the brain-derived neurotrophic factor (BDNF) gene have been
postulated to underlie the pathogenesis of neurodevelopmental, psychiatric, and …

Brain-derived neurotrophic factor is the most prevalent member of the nerve growth factor
family. Since its discovery in 1978, this enigmatic molecule has spawned more than 27,000 …

Background Fibromyalgia (FM) is a form of chronic pain disorder accompanied by several
tender points, fatigue, sleeping and mood disturbances, cognitive dysfunction, and memory …

We aimed to explore a path model identified using a structural equation model (SEM) which
best explains the multivariate contributions of sensitization, sensitivity, and emotional …

Pain is estimated to affect more than 20% of the global population, imposing incalculable
health and economic burdens. Effective pain management is crucial for individuals suffering …