Assisted reproductive technology: Short‐and long‐term outcomes

ME Graham, A Jelin, AH Hoon Jr… - … Medicine & Child …, 2023 - Wiley Online Library
Assisted reproductive technology (ART) includes fertility treatment in which either eggs or
embryos are handled outside a female's body to promote successful pregnancies and …

Offspring physiology following the use of IVM, IVF and ICSI: a systematic review and meta-analysis of animal studies

KH Beilby, E Kneebone, TJ Roseboom… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Since the birth of the first baby using IVF technology in 1978, over 10 million
children have been conceived via ART. Although most aspects of ARTs were developed in …

Maternal risk of cardiovascular disease after use of assisted reproductive technologies

MC Magnus, A Fraser, SE Håberg, K Rönö… - JAMA …, 2023 - jamanetwork.com
Importance The use of assisted reproductive technologies (ARTs) is steadily increasing
worldwide. The outcomes associated with treatment for an individual's long-term health …

DNA methylation in newborns conceived by assisted reproductive technology

SE Håberg, CM Page, Y Lee, HE Nustad… - Nature …, 2022 - nature.com
Assisted reproductive technology (ART) may affect fetal development through epigenetic
mechanisms as the timing of ART procedures coincides with the extensive epigenetic …

Advantages of vitrification preservation in assisted reproduction and potential influences on imprinted genes

H Chen, L Zhang, L Meng, L Liang, C Zhang - Clinical Epigenetics, 2022 - Springer
Cryopreservation has important application in assisted reproductive technology (ART). The
vitrification technique has been widely used in the cryopreservation of oocytes and embryos …

The cell biology of fertilization: Gamete attachment and fusion

KK Siu, VHB Serrão, A Ziyyat, JE Lee - Journal of Cell Biology, 2021 - rupress.org
Fertilization is defined as the union of two gametes. During fertilization, sperm and egg fuse
to form a diploid zygote to initiate prenatal development. In mammals, fertilization involves …

Epigenetics in the uterine environment: how maternal diet and ART may influence the epigenome in the offspring with long-term health consequences

I Peral-Sanchez, B Hojeij, DA Ojeda… - Genes, 2021 - mdpi.com
The societal burden of non-communicable disease is closely linked with environmental
exposures and lifestyle behaviours, including the adherence to a poor maternal diet from the …

Molecular markers: a new paradigm in the prediction of sperm freezability

M Ďuračka, F Benko, E Tvrdá - International journal of molecular sciences, 2023 - mdpi.com
For decades now, sperm cryopreservation has been a pillar of assisted reproduction in
animals as well as humans. Nevertheless, the success of cryopreservation varies across …

[HTML][HTML] Noncanonical imprinting: intergenerational epigenetic inheritance mediated by Polycomb complexes

A Inoue - Current Opinion in Genetics & Development, 2023 - Elsevier
Genomic imprinting is illustrative of intergenerational epigenetic inheritance. The passage of
parental genomes into the embryo is accompanied by epigenetic modifications, resulting in …

Unravelling the epigenetic impact: Oxidative stress and its role in male infertility-associated sperm dysfunction

G Sudhakaran, D Kesavan, K Kandaswamy… - Reproductive …, 2024 - Elsevier
Male infertility is a multifactorial condition influenced by epigenetic regulation, oxidative
stress, and mitochondrial dysfunction. Oxidative stress-induced damage leads to epigenetic …