The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

In recent years, ever-increasing scientific knowledge and modern high-tech advancements
in micro-and nano-scales fabrication technologies have impacted significantly on various …

The development of organs-on-chip (OoC) has revolutionized in vitro cell-culture
experiments by allowing a better mimicry of human physiology and pathophysiology that has …

Numerous cancer-associated deaths are owing to a lack of effective diagnostic and
therapeutic approaches. Microfluidic systems for analyzing a low volume of samples offer a …

Prenatal cannabis exposure (PCE) influences human brain development, but it is
challenging to model PCE using animals and current cell culture techniques. Here, we …

Regulation of cosmetic testing and poor predictivity of preclinical drug studies has spurred
efforts to develop new methods for systemic toxicity. Current in vitro assays do not fully …

Organ-on-a-chip academic research is in its blossom. Drug toxicity evaluation is a promising
area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a …

New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …

Simple Summary Cancer is one of the diseases with a high mortality rate worldwide. Of the
current strategies to study new diagnostic and treating tools, organs-on-chip are quite …

Traditional cell culture and animal models utilized for preclinical drug screening have led to
high attrition rates of drug candidates in clinical trials due to their low predictive power for …