With the increasing risk of invasive and life threating fungal infections, there is now a great
concern regarding the lower discovery rate of antifungal drugs in comparison to …

The treatment of invasive fungal infections remains challenging due to limitations in currently
available antifungal therapies including toxicity, interactions, restricted routes of …

Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …

Hydrazide–hydrazones possess a wide spectrum of bioactivity, including antibacterial,
antitubercular, antifungal, anticancer, anti-inflammatory, anticonvulsant, antidepressant …

In the past few decades, the development of heat shock protein 90 (Hsp90) inhibitors for
cancer treatment has not stopped. About twenty compounds have been evaluated in the …

RNAi technique was used to regulate Fusarium crown and root rot in tomatoes caused by F.
oxysporum f. sp. radicis-lycopersici (FORL), by targeting three essential genes namely …

Fungal skin infections are currently a major clinical problem due to their increased
occurrence and drug resistance. The treatment of fungal skin infections is based on …

Grapevine is one of the most important and globally widespread fruit species, with a high
impact on the economy of many countries but with an intense environmental effect …

Due to the limit of available treatments and the emergence of drug resistance in the clinic,
invasive fungal infections are an intractable problem with high morbidity and mortality. The …

Invasive fungal infections (particularly candidiasis) are emerging as severe infectious
diseases worldwide. Because of serious antifungal drug resistance, therapeutic efficacy of …