Endometriosis is a “mysterious” disease and its exact cause has not yet been established.
Among the etiological factors, congenital, environmental, epigenetic, autoimmune and …

The IL-6 family of cytokines consists of IL-6, IL-11, IL-27, IL-31, oncostatin M (OSM),
leukaemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), cardiotrophin 1 (CT-1) …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by a failure of
spontaneous resolution of inflammation. Although the pro-inflammatory cytokines and …

Type 1 diabetes is diagnosed at the end of a prodrome of β-cell autoimmunity. The disease
is most likely triggered at an early age by autoantibodies primarily directed against insulin or …

Abstract Ethnopharmacological relevance Paeoniae Radix Alba (PRA, called baishao in
China), the root of Paeonia lactiflora Pall., has shown a rich medicinal value for more than …

Cytokines play an important role in the immunopathogenesis of inflammatory bowel disease
(IBD), including Crohn's disease and ulcerative colitis, where they drive and regulate …

Shortly after intracerebral hemorrhage, neutrophils infiltrate the intracerebral hemorrhage-
injured brain. Once within the brain, neutrophils degranulate, releasing destructive …

Endometriosis refers to the growth of ectopic endometrial tissue outside the uterine cavity.
About 10–15% of female in reproductive age suffer from endometriosis. Several etiologies …

Autoimmune disorders are characterized by tissue damage, caused by self-reactivity of
different effectors mechanisms of the immune system, namely antibodies and T cells. Their …

Regulatory T cells (Tregs) are comprised of a heterogeneous population of cells that play a
vital role in suppressing inflammation and maintaining immune tolerance. Given the crucial …