Pancreatic islet transplantation has become an established approach to β-cell replacement
therapy for the treatment of insulin-deficient diabetes. Recent progress in techniques for islet …

The main goal of treatment for type 1 diabetes is to control glycaemia with insulin therapy to
reduce disease complications. For some patients, technological approaches to insulin …

Background Islet transplantation offers an effective treatment for selected people with type 1
diabetes and intractable hypoglycaemia. Long-term experience, however, remains limited …

Clinical studies on the treatment of type 1 diabetes with device-encapsulated pancreatic
precursor cells derived from human embryonic stem cells found that insulin output was …

BACKGROUND Residual C-peptide is detected in many people for years following the
diagnosis of type 1 diabetes; however, the physiologic significance of low levels of …

Whole-organ pancreas and islet transplantations are performed in a highly selected group of
patients with diabetes mellitus, primarily those with type 1 diabetes mellitus, complicated by …

Tremendous progress has been made over the last two decades in the field of pancreatic
beta cell replacement therapy as a curative measure for diabetes. Transplantation studies …

Over the last decades, the number of pancreas transplants has increased all over the world.
Since the first pancreas transplant in 1966, patient and graft survival after simultaneous …

OBJECTIVE The long-term outcome of allogenic islet transplantation is unknown. The aim of
this study was to evaluate the 10-year outcome of islet transplantation in patients with type 1 …

Pancreas transplantation (PTx) reestablishes an autoregulating source of endogenous
insulin responsive to normal feedback controls. In addition to achieving complete β-cell …