Thiol reactive probes and chemosensors

H Peng, W Chen, Y Cheng, L Hakuna, R Strongin… - Sensors, 2012 - mdpi.com
Thiols are important molecules in the environment and in biological processes. Cysteine
(Cys), homocysteine (Hcy), glutathione (GSH) and hydrogen sulfide (H2S) play critical roles …

Oxidative stress by inorganic nanoparticles

JK Tee, CN Ong, BH Bay, HK Ho… - Wiley Interdisciplinary …, 2016 - Wiley Online Library
Metallic and metallic oxide nanoparticles (NP s) have been increasingly used for various bio‐
applications owing to their unique physiochemical properties in terms of conductivity, optical …

Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis‐mediated cell death

M Guerrero‐Hue, C García‐Caballero… - The FASEB …, 2019 - Wiley Online Library
Acute kidney injury is a common complication of rhabdomyolysis. A better understanding of
this syndrome may be useful to identify novel therapeutic targets because there is no …

High fat/high glucose diet induces metabolic syndrome in an experimental rat model

S Moreno-Fernández, M Garcés-Rimón, G Vera… - Nutrients, 2018 - mdpi.com
Metabolic syndrome (MetS) is defined as a constellation of many metabolic disorders such
as hypertension, impaired glucose tolerance, dyslipidemia and obesity, being this last …

Characterization of superoxide-producing sites in isolated brain mitochondria

AP Kudin, NYB Bimpong-Buta, S Vielhaber… - Journal of Biological …, 2004 - ASBMB
Mitochondrial respiratory chain complexes I and III have been shown to produce superoxide
but the exact contribution and localization of individual sites have remained unclear. We …

A rhodamine-based fluorescent probe containing a Se− N bond for detecting thiols and its application in living cells

B Tang, Y Xing, P Li, N Zhang, F Yu… - Journal of the American …, 2007 - ACS Publications
Here we report a new rhodamine-based fluorescent probe containing a selenium− nitrogen
bond for detecting thiols based on the nucleophilic substitution of sulfhydryl. The probe was …

Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells

L Wu, BHJ Juurlink - Hypertension, 2002 - Am Heart Assoc
Methylglyoxal can yield advanced glycation end products via nonenzymatic glycation of
proteins. Whether methylglyoxal contributes to the pathogenesis of hypertension has not …

Specific uptake and genotoxicity induced by polystyrene nanobeads with distinct surface chemistry on human lung epithelial cells and macrophages

V Paget, S Dekali, T Kortulewski, R Grall, C Gamez… - PloS one, 2015 - journals.plos.org
Nanoparticle surface chemistry is known to play a crucial role in interactions with cells and
their related cytotoxic effects. As inhalation is a major route of exposure to nanoparticles, we …

Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

PS Baxter, KFS Bell, P Hasel, AM Kaindl… - Nature …, 2015 - nature.com
How the brain's antioxidant defenses adapt to changing demand is incompletely
understood. Here we show that synaptic activity is coupled, via the NMDA receptor …

Characterization of glutathione-S-transferases in zebrafish (Danio rerio)

B Glisic, I Mihaljevic, M Popovic, R Zaja, J Loncar… - Aquatic toxicology, 2015 - Elsevier
Abstract Glutathione-S-transferases (GSTs) are one of the key enzymes that mediate phase
II of cellular detoxification. The aim of our study was a comprehensive characterization of …