The apicoplast: now you see it, now you don't

GI McFadden, E Yeh - International journal for parasitology, 2017 - Elsevier
Parasites such as Plasmodium and Toxoplasma possess a vestigial plastid homologous to
the chloroplasts of algae and plants. The plastid (known as the apicoplast; for apicomplexan …

[HTML][HTML] Drug targets for resistant malaria: historic to future perspectives

S Kumar, TR Bhardwaj, DN Prasad… - Biomedicine & …, 2018 - Elsevier
New antimalarial targets are the prime need for the discovery of potent drug candidates. In
order to fulfill this objective, antimalarial drug researches are focusing on promising targets …

The algal past and parasite present of the apicoplast

GG van Dooren, B Striepen - Annual review of microbiology, 2013 - annualreviews.org
Plasmodium and Toxoplasma are genera of apicomplexan parasites that infect millions of
people each year. The former causes malaria, and the latter causes neurotropic infections …

[HTML][HTML] Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts

MJ Shears, CY Botté, GI McFadden - Molecular and biochemical …, 2015 - Elsevier
The malaria parasite Plasmodium possesses a relict, non-photosynthetic plastid known as
the apicoplast. The apicoplast is essential for parasite survival, and harbors several plant …

[HTML][HTML] Strawberry proteome responses to controlled hot and cold stress partly mimic post-harvest storage temperature effects on fruit quality

J Lv, T Zheng, Z Song, T Pervaiz, T Dong… - Frontiers in …, 2022 - frontiersin.org
To determine the effect of different temperature on strawberry after harvest, physiological
indicator analysis and proteomics analysis were conducted on ripened strawberry (“Sweet …

The transportome of the malaria parasite

RE Martin - Biological Reviews, 2020 - Wiley Online Library
Membrane transport proteins, also known as transporters, control the movement of ions,
nutrients, metabolites, and waste products across the membranes of a cell and are central to …

[HTML][HTML] The metabolic pathways and transporters of the plastid organelle in Apicomplexa

J Kloehn, CEM Lacour, D Soldati-Favre - Current opinion in microbiology, 2021 - Elsevier
Highlights•The apicoplast critically participates in metabolism of disease-causing
apicomplexans.•T. gondii overcomes loss of apicoplast-resident pathways through uptake of …

Inhibition of malaria parasite Plasmodium falciparum development by crotamine, a cell penetrating peptide from the snake venom

SEC Maluf, C Dal Mas, EB Oliveira, PM Melo… - Peptides, 2016 - Elsevier
We show here that crotamine, a polypeptide from the South American rattlesnake venom
with cell penetrating and selective anti-fungal and anti-tumoral properties, presents a potent …

Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity

Y Lee, T Nishizawa, M Takemoto, K Kumazaki… - Nature plants, 2017 - nature.com
The triose-phosphate/phosphate translocator (TPT) catalyses the strict 1: 1 exchange of
triose-phosphate, 3-phosphoglycerate and inorganic phosphate across the chloroplast …

Localization and Evolution of Putative Triose Phosphate Translocators in the Diatom Phaeodactylum tricornutum

D Moog, SA Rensing, JM Archibald… - Genome biology and …, 2015 - academic.oup.com
The establishment of a metabolic connection between host and symbiont is a crucial step in
the evolution of an obligate endosymbiotic relationship. Such was the case in the evolution …