That humans in endemic areas become immune to malaria offers encouragement to the
idea of developing protective vaccines. However natural immunity is relatively inefficient …

Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …

Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are
important targets of naturally acquired immunity against malaria, but their high number and …

Plasmodium falciparum is the major cause of malaria globally and is transmitted by
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …

Background The variant surface antigen family Plasmodium falciparum erythrocyte
membrane protein-1 (PfEMP1) is an important target for protective immunity and is …

Parasite-encoded variant surface antigens (VSAs) like the var gene–encoded Plasmodium
falciparum erythrocyte membrane protein 1 (PfEMP1) family are responsible for antigenic …

Malaria parasites cause much morbidity and mortality to their human hosts. From our
evolutionary perspective, this is because virulence is positively associated with parasite …

The var gene family of Plasmodium falciparum encodes the variant surface antigen
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 is considered …

In areas of endemic parasite transmission, protective immunity to Plasmodium falciparum
malaria is acquired over several years with numerous disease episodes. Acquisition of Abs …

Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …