Notable changes in lung cancer epidemiology and prevention have occurred over the past
decade owing to changes in smoking patterns, groundbreaking advances in our …

Glucocorticoids are steroid hormones that regulate a host of cellular and physiological
functions. However, they are arguably best known for their potent anti-inflammatory …

The glucocorticoid receptor (GR) regulates gene expression, governing aspects of
homeostasis, but is also involved in cancer. Pharmacological GR activation is frequently …

Background Evidence regarding the risk of cancer development after asthma diagnosis is
controversial and inconclusive. Objective This study sought to determine whether asthma is …

Purpose Observational studies using computerized healthcare databases have become
popular to investigate the potential effectiveness of old drugs for new indications. Many of …

Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Lung cancer and chronic obstructive pulmonary disease (COPD) often co-occur, and
individuals with COPD are at a higher risk of developing lung cancer. While the underlying …

The World Health Organisation reported COPD to be the third leading cause of death
globally in 2019, and in 2020, the most common cause of cancer death was lung cancer; …

Our starting point is that relatively new findings into the pathogenesis and pathophysiology
of airway disease in smokers that lead to chronic obstructive pulmonary disease (COPD) …

Chronic obstructive pulmonary disease (COPD) and lung cancer are common global causes
of morbidity and mortality. Because both diseases share several predisposing risks, the 2 …