Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain
G Ramesh, AG MacLean… - Mediators of inflammation, 2013 - Wiley Online Library
Cytokines and chemokines are proteins that coordinate the immune response throughout
the body. The dysregulation of cytokines and chemokines is a central feature in the …
the body. The dysregulation of cytokines and chemokines is a central feature in the …
[HTML][HTML] Cytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases
G Lepennetier, Z Hracsko, M Unger… - Journal of …, 2019 - Springer
Background Cytokines play multiple roles during neuro-inflammatory processes and several
cytokines have been studied in the context of specific diseases. This study provides a …
cytokines have been studied in the context of specific diseases. This study provides a …
[HTML][HTML] Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria
CC John, A Panoskaltsis-Mortari… - The American journal …, 2008 - ncbi.nlm.nih.gov
Cerebrospinal fluid (CSF) and serum levels of 12 cytokines or chemokines important in
central nervous system (CNS) infections were measured in 76 Ugandan children with …
central nervous system (CNS) infections were measured in 76 Ugandan children with …
High levels of inflammatory chemokines and cytokines in joint fluid and synovial tissue throughout the course of antibiotic‐refractory Lyme arthritis
JJ Shin, LJ Glickstein, AC Steere - Arthritis & Rheumatism, 2007 - Wiley Online Library
Objective To investigate the possible role of chemokines and cytokines in the pathogenesis
of Lyme arthritis. Methods Using cytometric bead array and flow cytometry techniques …
of Lyme arthritis. Methods Using cytometric bead array and flow cytometry techniques …
[HTML][HTML] Cerebrospinal fluid cytokines in Lyme neuroborreliosis
A Pietikäinen, M Maksimow, T Kauko, S Hurme… - Journal of …, 2016 - Springer
Background Lyme neuroborreliosis (LNB) is one of the manifestations of Lyme disease.
Although it is known that immune reaction of LNB patients is dominated by Th1 and Th2 …
Although it is known that immune reaction of LNB patients is dominated by Th1 and Th2 …
Interaction of the Lyme disease spirochete Borrelia burgdorferi with brain parenchyma elicits inflammatory mediators from glial cells as well as glial and neuronal …
G Ramesh, JT Borda, J Dufour, D Kaushal… - The American journal of …, 2008 - Elsevier
Lyme neuroborreliosis, caused by the spirochete Borrelia burgdorferi, often manifests by
causing neurocognitive deficits. As a possible mechanism for Lyme neuroborreliosis, we …
causing neurocognitive deficits. As a possible mechanism for Lyme neuroborreliosis, we …
[HTML][HTML] A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi
G Ramesh, S Benge, B Pahar, MT Philipp - Journal of neuroinflammation, 2012 - Springer
Background Inflammation caused by the Lyme disease spirochete B. burgdorferi is an
important factor in the pathogenesis of Lyme neuroborreliosis. Our central hypothesis is that …
important factor in the pathogenesis of Lyme neuroborreliosis. Our central hypothesis is that …
The Antibiotics Doxycycline and Minocycline Inhibit the Inflammatory Responses to the Lyme Disease Spirochete Borrelia burgdorferi
ALF Bernardino, D Kaushal… - The Journal of infectious …, 2009 - academic.oup.com
Tetracyclines moderate inflammatory responses of various etiologies. We hypothesized that
tetracyclines, in addition to their antimicrobial function, could exert control over the …
tetracyclines, in addition to their antimicrobial function, could exert control over the …
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis
ALF Bernardino, TA Myers, X Alvarez… - Infection and …, 2008 - Am Soc Microbiol
Lyme neuroborreliosis is likely caused by inflammatory effects of the tick-borne spirochete
Borrelia burgdorferi on the nervous system. Microglia, the resident macrophage cells within …
Borrelia burgdorferi on the nervous system. Microglia, the resident macrophage cells within …
Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation
ABSTRACT Interleukin-10 (IL-10) modulates inflammatory responses elicited in vitro and in
vivo by Borrelia burgdorferi, the Lyme disease spirochete. How IL-10 modulates these …
vivo by Borrelia burgdorferi, the Lyme disease spirochete. How IL-10 modulates these …