Forkhead box O (FOXO) transcription factors regulate diverse biological processes, affecting
development, metabolism, stem cell maintenance and longevity. They have also been …

The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

Resveratrol (3, 5, 4′-trihydroxystilbene; RSV) is a natural nonflavonoid polyphenol present
in many species of plants, particularly in grapes, blueberries, and peanuts. Several in vitro …

Cancer stem cells (CSCs) are the main culprits involved in therapy resistance and disease
recurrence in colorectal carcinoma (CRC). Results using cell culture, animal models and …

Background Fermented food has been emerging as a new value-added category for the
food industry and consumers. Blueberries (Vaccinium species) are known as “superfoods” …

Combination therapy consists in the simultaneous administration of a conventional
chemotherapy drug (or sometimes, a radiotherapy protocol) together with one or more …

Colorectal cancer (CRC) is one of the deadliest human malignancies worldwide. Several
molecular pathways have been demonstrated to be involved in the initiation and …

Supplementation with natural compounds found in fruits and vegetables has long been
associated with a reduced risk of several types of cancer. Pterostilbene is a natural …

A substantial increase in colorectal cancer (CRC)–associated fatalities can be attributed to
tumor recurrence and multidrug resistance. Traditional treatment options, including radio …

Colorectal cancer is one of the most common causes of cancer death worldwide. In patients
with metastatic colorectal cancer, combination treatment with several anti-cancer drugs is …