The present volume is the third in a trilogy that documents naturally occurring
organohalogen compounds, bringing the total number—from fewer than 25 in 1968—to …

Genome mining and biocatalytic modification of chemical structures are critical methods to
develop new antibiotics. In this study, eight new fasamycins (3, 4, 6, and 8–12) along with …

The formicamycins are promising antibiotics first identified in Streptomyces formicae KY5,
which produces the compounds at low levels. Here, we show that by understanding the …

The genome of Streptomyces indonesiensis is highly enriched with cryptic biosynthetic gene
clusters (BGCs). The majority of these cryptic BGCs are transcriptionally silent in normal …

Natural products are important sources for drug development, and the accurate prediction of
their structures assembled by modular proteins is an area of great interest. In this study, we …

LCMS-guided screening of a library of biosynthetically talented bacteria and fungi identified
Streptomyces sp. MST-144321 as a prolific producer of chlorinated metabolites. We isolated …

Covering: September 1964 to June 2023Bacteria and fungi living in symbiosis with insects
have been studied over the last sixty years and found to be important sources of bioactive …

Covering 2009–2022. Phenylnaphthacenoid polyketides have gained significant interest in
recent years owing to their potent antibacterial and anticancer activities. Notably, more than …

Actinomycete bacteria derived from marine environments are a good source of natural
products with diverse biological activities such as cytotoxicity, antiviral, and antimicrobial …

Bacterial secondary metabolites represent an invaluable source of bioactive molecules for
the pharmaceutical and agrochemical industries. Although screening campaigns for the …