New insights into metronomic chemotherapy-induced immunoregulation

YB Hao, SY Yi, J Ruan, L Zhao, KJ Nan - Cancer letters, 2014 - Elsevier
Chemotherapy is the mainstay of treatment in mid-advanced tumors. Considering their
toxicity on hematopoietic cells, chemotherapeutics are often considered as …

[HTML][HTML] Synergic effect of PD-1 blockade and endostar on the PI3K/AKT/mTOR-mediated autophagy and angiogenesis in Lewis lung carcinoma mouse model

J Wu, X Zhao, Q Sun, Y Jiang, W Zhang, J Luo… - Biomedicine & …, 2020 - Elsevier
Background Immunotherapy has been shown to be effective as a first-line treatment option
for non-small cell lung cancer (NSCLC) patients. Unfortunately, it has failed to acquire an …

The dual role of NK cells in antitumor reactions triggered by ionizing radiation in combination with hyperthermia

P Finkel, B Frey, F Mayer, K Bösl, N Werthmöller… - …, 2016 - Taylor & Francis
Classical tumor therapy consists of surgery, radio (RT)-and/or chemotherapy. Additive
immunotherapy has gained in impact and antitumor in situ immunization strategies are …

Wogonin inhibits tumor-derived regulatory molecules by suppressing STAT3 signaling to promote tumor immunity

W Xiao, K Wu, M Yin, S Han, Y Ding… - Journal of …, 2015 - journals.lww.com
Wogonin exerts effective antitumor activities through direct cytotoxicity against cancer cells
and indirect immune modulation. However, the molecular mechanisms of these activities …

Peptide-based therapeutic cancer vaccines

CJM Melief - Oncoimmunology: A Practical Guide for Cancer …, 2018 - Springer
Peptides have attracted much interest as a platform for the induction of therapeutic T cell
responses, ever since the discovery of MHC-presented protein fragments (peptides) as the …

Evaluation of immune cell infiltrates and expression of cytokines/biological molecules in the microenvironment of tumours and tumour-draining axillary lymph nodes in …

V Kaewkangsadan - 2016 - eprints.nottingham.ac.uk
Background Neoadjuvant chemotherapy (NAC) is being used as first line treatment in
women with large and locally advanced breast cancers (LLABCs). However, the response to …

Les cellules souches mésenchymateuses: cheval de Troie dans une thérapie gène suicide

I Amara - 2016 - theses.hal.science
Les chimiothérapies actuelles manquent encore souvent d'efficacité et présentent de
nombreux effets secondaires délétères. De ce fait, de nouvelles stratégies émergent, avec …