The microbiota-gut-brain axis: from motility to mood

KG Margolis, JF Cryan, EA Mayer - Gastroenterology, 2021 - Elsevier
The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

Gut microbial metabolites as multi-kingdom intermediates

KA Krautkramer, J Fan, F Bäckhed - Nature Reviews Microbiology, 2021 - nature.com
The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

The microbiota-gut-brain axis in sleep disorders

Z Wang, Z Wang, T Lu, W Chen, W Yan, K Yuan… - Sleep medicine …, 2022 - Elsevier
Sleep is a complex physiological process and is a critical determinant of physical and
mental health. In the past decades, significant progress has been made in understanding …

Gut bacteria and neurotransmitters

LMT Dicks - Microorganisms, 2022 - mdpi.com
Gut bacteria play an important role in the digestion of food, immune activation, and
regulation of entero-endocrine signaling pathways, but also communicate with the central …

Gut microbiome-wide association study of depressive symptoms

D Radjabzadeh, JA Bosch, AG Uitterlinden… - Nature …, 2022 - nature.com
Depression is one of the most poorly understood diseases due to its elusive pathogenesis.
There is an urgency to identify molecular and biological mechanisms underlying depression …

Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial

P Tian, Y Chen, H Zhu, L Wang, X Qian, R Zou… - Brain, behavior, and …, 2022 - Elsevier
Objective Psychobiotics, as a novel class of probiotics mainly acting on the gut-brain axis,
have shown promising prospects in treating psychiatric disorders. Bifidobacterium breve …

Gut microbiota Turicibacter strains differentially modify bile acids and host lipids

JB Lynch, EL Gonzalez, K Choy, KF Faull… - Nature …, 2023 - nature.com
Bacteria from the Turicibacter genus are prominent members of the mammalian gut
microbiota and correlate with alterations in dietary fat and body weight, but the specific …

Strain-specific gut microbial signatures in type 2 diabetes identified in a cross-cohort analysis of 8,117 metagenomes

Z Mei, F Wang, A Bhosle, D Dong, R Mehta, A Ghazi… - Nature medicine, 2024 - nature.com
The association of gut microbial features with type 2 diabetes (T2D) has been inconsistent
due in part to the complexity of this disease and variation in study design. Even in cases in …

[HTML][HTML] Gut microbial dysbiosis in the pathogenesis of gastrointestinal dysmotility and metabolic disorders

R Singh, H Zogg, L Wei, A Bartlett… - Journal of …, 2021 - ncbi.nlm.nih.gov
Of all microorganisms in the human body, the largest and most complex population resides
in the gastrointestinal (GI) tract. The gut microbiota continuously adapts to the host …

Neuromicrobiology, an emerging neurometabolic facet of the gut microbiome?

S Miri, JD Yeo, S Abubaker, R Hammami - Frontiers in Microbiology, 2023 - frontiersin.org
The concept of the gut microbiome is emerging as a metabolic interactome influenced by
diet, xenobiotics, genetics, and other environmental factors that affect the host's absorption …