Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm
Y Nakamura, A Kawazoe, F Lordick… - Nature reviews Clinical …, 2021 - nature.com
Advances in cancer biology and sequencing technology have enabled the selection of
targeted and more effective treatments for individual patients with various types of solid …
targeted and more effective treatments for individual patients with various types of solid …
[HTML][HTML] HER2 testing in gastric cancer: An update
LF Abrahao-Machado… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Human epidermal growth factor receptor 2 (HER2) overexpression is increasingly
recognized as a frequent molecular abnormality in gastric and gastroesophageal cancer …
recognized as a frequent molecular abnormality in gastric and gastroesophageal cancer …
Lapatinib Plus Paclitaxel Versus Paclitaxel Alone in the Second-Line Treatment of HER2-Amplified Advanced Gastric Cancer in Asian Populations: TyTAN—A …
Purpose In Asian countries, paclitaxel once per week is used as second-line treatment in
advanced gastric cancer, including human epidermal growth factor receptor 2 (HER2) …
advanced gastric cancer, including human epidermal growth factor receptor 2 (HER2) …
The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis
MM Moasser - Oncogene, 2007 - nature.com
The year 2007 marks exactly two decades since Human Epidermal Growth Factor Receptor-
2 (HER2) was functionally implicated in the pathogenesis of human breast cancer. This …
2 (HER2) was functionally implicated in the pathogenesis of human breast cancer. This …
Assessment of a HER2 scoring system for gastric cancer: results from a validation study
M Hofmann, O Stoss, D Shi, R Büttner… - …, 2008 - Wiley Online Library
Aims: Human epidermal growth factor receptor 2 (HER2) overexpression/amplification is
implicated in the development of various solid tumour types. Validated methods and scoring …
implicated in the development of various solid tumour types. Validated methods and scoring …
[HTML][HTML] HER2-positive gastric cancer
N Boku - Gastric cancer, 2014 - Springer
Human epidermal growth factor receptor 2 (HER2) is involved in the pathogenesis and poor
outcomes of several types of cancer, including advanced gastric and gastroesophageal …
outcomes of several types of cancer, including advanced gastric and gastroesophageal …
[HTML][HTML] HER2 diagnostics in gastric cancer—guideline validation and development of standardized immunohistochemical testing
J Rüschoff, M Dietel, G Baretton, S Arbogast, A Walch… - Virchows Archiv, 2010 - Springer
Trastuzumab-based therapy has been shown to confer overall survival benefit in HER2-
positive patients with advanced gastric cancer in a large multicentric trial (ToGA study) …
positive patients with advanced gastric cancer in a large multicentric trial (ToGA study) …
[HTML][HTML] An organoid-based preclinical model of human gastric cancer
NG Steele, J Chakrabarti, J Wang, J Biesiada… - Cellular and molecular …, 2019 - Elsevier
Background & Aims Our goal was to develop an initial study for the proof of concept whereby
gastric cancer organoids are used as an approach to predict the tumor response in …
gastric cancer organoids are used as an approach to predict the tumor response in …
[HTML][HTML] Clinical practice guidelines for gastric cancer in Korea: an evidence-based approach
JH Lee, JG Kim, HK Jung, JH Kim… - Journal of gastric …, 2014 - synapse.koreamed.org
Although gastric cancer is quite common in Korea, the treatment outcome is relatively
favorable compared to those in western countries. However, there are currently no Korean …
favorable compared to those in western countries. However, there are currently no Korean …
[HTML][HTML] Targeted therapies for gastric cancer: failures and hopes from clinical trials
M Apicella, S Corso, S Giordano - Oncotarget, 2017 - ncbi.nlm.nih.gov
Gastric cancer is the third leading cause of cancer mortality worldwide. As surgery is the only
curative treatment strategy and conventional chemotherapy has shown limited efficacy-with …
curative treatment strategy and conventional chemotherapy has shown limited efficacy-with …