Challenges in drug delivery to the brain: nature is against us

S Krol - Journal of Controlled Release, 2012 - Elsevier
Nanomedicine is a fast evolving field involving nanoparticles or nanostructures for medical
applications. Especially in the underdeveloped field of drug delivery to the brain, there are …

Protein–material interactions: From micro-to-nano scale

TS Tsapikouni, YF Missirlis - Materials Science and Engineering: B, 2008 - Elsevier
The article presents a survey on the significance of protein–material interactions, the
mechanisms which control them and the techniques used for their study. Protein–surface …

Hydroxylation structure of quartz surface and its molecular hydrophobicity

H Zhang, Z Xu, W Sun, Y Zhu, D Chen, C Zhang - Applied Surface Science, 2023 - Elsevier
The hydroxylation behavior of water on the quartz surface plays an important role in many
fields. In this paper, the surface hydroxylation behavior of quartz and the molecular …

Design and evaluation of collagen-inspired mineral-hydrogel nanocomposites for bone regeneration

A Patel, SH Zaky, K Schoedel, H Li, V Sant, E Beniash… - Acta biomaterialia, 2020 - Elsevier
Bone loss due to trauma and tumors remains a serious clinical concern. Due to limited
availability and disease transmission risk with autografts and allografts, calcium phosphate …

Effect of hydration forces on protein fouling of ultrafiltration membranes: the role of protein charge, hydrated ion species, and membrane hydrophilicity

R Miao, L Wang, M Zhu, D Deng, S Li… - Environmental …, 2017 - ACS Publications
To investigate the influence of hydration forces on the protein fouling of membranes and the
major influence factors of hydration forces during the ultrafiltration process, bovine serum …

Non-specific adhesion on biomaterial surfaces driven by small amounts of protein adsorption

S Kalasin, MM Santore - Colloids and Surfaces B: Biointerfaces, 2009 - Elsevier
This work explores how long-range non-specific interactions, resulting from small amounts
of adsorbed fibrinogen, potentially influence bioadhesion. Such non-specific interactions …

Polymeric nanocomposite hydrogel scaffolds in craniofacial bone regeneration: a comprehensive review

MH Bashir, NS Korany, DBE Farag, MMS Abbass… - Biomolecules, 2023 - mdpi.com
Nanocomposite biomaterials combine a biopolymeric matrix structure with nanoscale fillers.
These bioactive and easily resorbable nanocomposites have been broadly divided into …

Effect of protein–protein interactions on translational diffusion of spheroidal proteins

AM Kusova, AE Sitnitsky, VN Uversky… - International Journal of …, 2022 - mdpi.com
One of the commonly accepted approaches to estimate protein–protein interactions (PPI) in
aqueous solutions is the analysis of their translational diffusion. The present review article …

Distribution of sialic acids on mucins and gels: a defense mechanism

SC Baos, DB Phillips, L Wildling, TJ McMaster… - Biophysical journal, 2012 - cell.com
Moist mucosal epithelial interfaces that are exposed to external environments are dominated
by sugar epitopes, some of which (eg, sialic acids) are involved in host defense. In this …

The role of pH and ionic Strength in the attraction–repulsion balance of fibrinogen interactions

AM Kusova, AE Sitnitsky, YF Zuev - Langmuir, 2021 - ACS Publications
Fibrinogen (Fg) self-assembly is sensitive to the physicochemical properties of an
environment like pH and ionic strength. These parameters tune the direction and strength of …