Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in
virtually all metozoan cells and serve a wide variety of functions ranging from gene …

Store-operated calcium entry is a central mechanism in cellular calcium signalling and in
maintaining cellular calcium balance. This review traces the history of research on store …

Signaling through the store-operated Ca2+ release-activated Ca2+ (CRAC) channel
regulates critical cellular functions, including gene expression, cell growth and …

Store-operated calcium (Ca2+) entry (SOCE) occurs through a widely distributed family of
ion channels activated by the loss of Ca2+ from the endoplasmic reticulum (ER). The best …

Two defining functional features of ion channels are ion selectivity and channel gating. Ion
selectivity is generally considered an immutable property of the open channel structure …

Calcium dynamics in astrocytes represent a fundamental signal that through gliotransmitter
release regulates synaptic plasticity and behaviour. Here we present a longitudinal study in …

Abstract A primary calcium (Ca 2+) entry pathway into non-excitable cells is through the
store-operated Ca 2+ release activated Ca 2+(CRAC) channel. Ca 2+ entry into cells is …

Ca2+-dependent inactivation (CDI) is a key regulator and hallmark of the Ca2+ release-
activated Ca2+ (CRAC) channel, a prototypic store-operated Ca2+ channel. Although the …

The entry of calcium into the mammary epithelial cell from the maternal plasma (ie, calcium
influx mechanisms) during lactation is poorly understood. As alterations in calcium channels …

Store-operated Ca2+ entry depends critically on physical interactions of the endoplasmic
reticulum (ER) Ca2+ sensor stromal interaction molecule 1 (STIM1) and the Ca2+ release …