[HTML][HTML] Cytokines in inflammatory disease

S Kany, JT Vollrath, B Relja - International journal of molecular sciences, 2019 - mdpi.com
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …

[HTML][HTML] IL-10 family cytokines IL-10 and IL-22: from basic science to clinical translation

W Ouyang, A O'Garra - Immunity, 2019 - cell.com
Cytokines are among the most important effector and messenger molecules in the immune
system. They profoundly participate in immune responses during infection and inflammation …

Regulation and functions of the IL-10 family of cytokines in inflammation and disease

W Ouyang, S Rutz, NK Crellin, PA Valdez… - Annual review of …, 2011 - annualreviews.org
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …

Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases

M Akdis, S Burgler, R Crameri, T Eiwegger… - Journal of allergy and …, 2011 - Elsevier
Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

Biology of interleukin-10

R Sabat, G Grütz, K Warszawska, S Kirsch… - Cytokine & growth factor …, 2010 - Elsevier
Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides
TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes …

Development, cytokine profile and function of human interleukin 17–producing helper T cells

NJ Wilson, K Boniface, JR Chan, BS McKenzie… - Nature …, 2007 - nature.com
TH-17 cells are a distinct lineage of proinflammatory T helper cells that are essential for
autoimmune disease. In mice, commitment to the TH-17 lineage is dependent on …

Interferon-lambda: a new addition to an old family

RP Donnelly, SV Kotenko - Journal of Interferon & Cytokine …, 2010 - liebertpub.com
The discovery and initial description of the interferon-λ (IFN-λ) family in early 2003 opened
an exciting new chapter in the field of IFN research. There are 3 IFN-λ genes that encode 3 …

Biology of interleukin-22

K Wolk, E Witte, K Witte, K Warszawska… - Seminars in …, 2010 - Springer
Abstract Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an
important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell …

Interferons α and λ inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics

T Marcello, A Grakoui, G Barba–Spaeth, ES Machlin… - Gastroenterology, 2006 - Elsevier
Background & Aims: Hepatitis C virus (HCV) is a major cause of chronic liver disease,
cirrhosis, and hepatocellular carcinoma. Current therapy with pegylated interferon α (IFN-α) …

Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma

J Iqbal, DD Weisenburger, TC Greiner… - Blood, The Journal …, 2010 - ashpublications.org
Peripheral T-cell lymphoma (PTCL) is often challenging to diagnose and classify. Gene
expression profiling was performed on 144 cases of PTCL and natural killer cell lymphoma …