Atropisomerism is a stereochemical behavior portrayed by three-dimensional molecules that
bear rotationally restricted σ bond. Akin to the well-represented point-chiral molecules …

Enantiomers, where chirality arises from restricted rotation around a single bond, are
atropisomers. Due to the unique nature of the origins of their chirality, synthetic strategies to …

This tutorial review provides a systematic overview of the available methodologies for the
atroposelective transformation of (heterobiaryl) biaryl precursors toward the synthesis of …

The first highly atroposelective construction of N− N axially chiral indole scaffolds was
established via a new strategy of de novo ring formation. This strategy makes use of the …

Conspectus Arising from the restricted rotation of a single bond caused by steric or
electronic effects, atropisomerism is one of the few fundamental categories for molecules to …

Catalytic dynamic kinetic asymmetric transformation (DyKAT) provides a powerful tool to
access chiral stereoisomers from racemic substrates. Such transformation has been widely …

Rhodium (III)-catalyzed enantioselective oxidative C–H/C–H cross-coupling reaction
between two arenes is disclosed. With the combination of a chiral CpRh (III) complex and a …

Over the past few decades, the Buchwald–Hartwig reaction has emerged as a powerful tool
for forging C− N bonds, and has been vital to the pharmaceuticals, materials, and catalysis …

Conjugate addition is among the most important synthetic protocols for constructing carbon
skeletons and is widely used to synthesize natural products and drugs. However …

Atroposelective synthesis of axially chiral biaryls by palladium‐catalyzed C− H olefination,
using tert‐leucine as an inexpensive, catalytic, and transient chiral auxiliary, has been …