Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

Tumor necrosis factor alpha (TNF‐α) is a proinflammatory cytokine that exerts both
homeostatic and pathophysiological roles in the central nervous system. In pathological …

The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …

The brain is a singular organ of unique biological complexity that serves as the command
center for cognitive and motor function. As such, this specialized system also possesses a …

The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC (for
example, the Smith Papyrus), and zinc has apparently been used fairly steadily throughout …

The proinflammatory cytokine tumor necrosis factor-α (TNFα) causes a rapid exocytosis of
AMPA receptors in hippocampal pyramidal cells and is constitutively required for the …

The most striking features of diabetic retinopathy are the vascular abnormalities that are
apparent by fundus examination. There is also strong evidence that diabetes causes …

Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of
legal blindness in working-age adults. The clinical hallmarks of DR include increased …